Endothelium and Vascular Smooth Muscle Cells in the Context of Uremia

被引：23

作者：

Guenthner, Thomas ^{[1
]}

Jankowski, Vera ^{[1
]}

Kretschmer, Axel ^{[2
]}

Nierhaus, Marc ^{[1
]}

van der Giet, Markus ^{[1
]}

Zidek, Walter ^{[1
]}

Jankowski, Joachim ^{[1
]}

机构：

[1] Charite, Med Klin 4, CBF, D-12200 Berlin, Germany

[2] Bayer Schering Pharma, Global Drug Discovery Translat Med & Biomarkers, Wuppertal, Germany

来源：

SEMINARS IN DIALYSIS | 2009年 / 22卷 / 04期

关键词：

CHRONIC KIDNEY-DISEASE; NITRIC-OXIDE; ASYMMETRICAL DIMETHYLARGININE; OXIDATIVE STRESS; GROWTH-FACTOR; ANGIOTENSIN; RISK; ADRENOMEDULLIN; PROLIFERATION; ANGIOGENESIS;

D O I：

10.1111/j.1525-139X.2009.00594.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

It is obvious that retention of uremic toxins leads to endothelial dysfunction, which in turn initiates proliferation of vascular smooth muscle cells. Yet, the entity of the cascade of pathomechanisms has not sufficiently been elucidated. Endothelial dysfunction inevitably and irreversibly leads to progressive cardiovascular dysfunction and thereby represents the beginning of a life-limiting cascade. This review highlights important findings in this field.

引用

页码：428 / 432

页数：5

共 50 条

[1] Endothelium-dependent hyperpolarization of vascular smooth muscle cells
Félétou, M
Vanhoute, PM
ACTA PHARMACOLOGICA SINICA, 2000, 21 (01) : 1 - 18
[2] Organization of vascular smooth muscle cells by endothelium-derived protein
Oike, Masahiro
Kimura, Chiwaka
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, 115 : 157P - 157P
[3] Photorelaxation of vascular smooth muscle: Role of the endothelium
Flitney, FW
Megson, IL
VASCULAR ENDOTHELIUM: SOURCE AND TARGET OF INFLAMMATORY MEDIATORS, 2001, 330 : 290 - 291
[4] Endothelium-independent conversion of angiotensin I by vascular smooth muscle cells
Florence Coulet
Walter Gonzalez
Christophe Boixel
Olivier Meilhac
Maria E. Pueyo
Jean-Baptiste Michel
Cell and Tissue Research, 2001, 303 : 227 - 234
[5] Endothelium-independent conversion of angiotensin I by vascular smooth muscle cells
Coulet, F
Gonzalez, W
Boixel, C
Meilhac, O
Pueyo, ME
Michel, JB
CELL AND TISSUE RESEARCH, 2001, 303 (02) : 227 - 234
[6] CO-CULTURE OF VASCULAR ENDOTHELIUM AND SMOOTH-MUSCLE CELLS - EFFECTS OF HEPARIN ON SMOOTH-MUSCLE PROLIFERATION
WARREN, HB
OCONNOR, SE
EISENHAURE, BM
DAVIES, PF
JOURNAL OF CELL BIOLOGY, 1983, 97 (05): : A87 - A87
[7] THE ENDOTHELIUM - MODULATOR OF VASCULAR SMOOTH-MUSCLE TONE
VANHOUTTE, PM
NEW ENGLAND JOURNAL OF MEDICINE, 1988, 319 (08): : 512 - 513
[8] VASCULAR BIOLOGY: ENDOTHELIUM AND SMOOTH MUSCLE CELLS. MEMBRANE CONTACT SITES IN ENDOTHELIAL CELLS
Kivela, A.
Olkkonen, V.
ATHEROSCLEROSIS, 2016, 252 : E160 - E161
[9] MODULATION OF VASCULAR SMOOTH-MUSCLE CONTRACTION BY THE ENDOTHELIUM
VANHOUTTE, PM
RUBANYI, GM
MILLER, VM
HOUSTON, DS
ANNUAL REVIEW OF PHYSIOLOGY, 1986, 48 : 307 - 320
[10] The endothelium: influencing vascular smooth muscle in many ways
Triggle, Chris R.
Samuel, Samson Mathews
Ravishankar, Shalini
Marei, Isra
Arunachalam, Gnanapragasam
Ding, Hong
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2012, 90 (06) : 713 - 738

← 1 2 3 4 5 →