Selective transition metal-free aroylation of diarylmethanes with 2-acyl-imidazolium salts via acyl C-C bond cleavage

被引：4
|
作者：
Zou, Dong [1 ]
Gan, Li-She [2 ]
Yang, Fan [1 ]
Wang, Jia-Min [1 ]
Li, Lin-Lin [1 ]
Li, Jie [1 ]
机构：
[1] Zhejiang Univ City Coll, Sch Med, Dept Pharm, 48 Huzhou Rd, Hangzhou 310015, Peoples R China
[2] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Peoples R China
来源：
TETRAHEDRON LETTERS | 2020年 / 61卷 / 49期
基金：
中国国家自然科学基金;
关键词：
1,2,2-Triarylethanones; Transition metal-free; Aroylation; 2-Acyl-imidazolium salts; Diarylmethane; CATALYZED ALPHA-ARYLATION; C(SP(3))-H ARYLATION; PHENYL KETONES; AMIDES; ACTIVATION; DEOXYBENZOINS; TRIARYLMETHANES; SUBSTITUTION; DERIVATIVES; REACTIVITY;
D O I：
10.1016/j.tetlet.2020.152532
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly chemoselective method is reported for the aroylation of simple diarylmethane derivatives via direct acyl C-C cleavage with 2-acyl-imidazolium salts under transition metal-free conditions. This represents a straightforward way to access a variety of sterically and electronically diverse 1,2,2-triarylethanones, a class of compounds with biological activities and various applications. (C) 2020 Elsevier Ltd. All rights reserved.
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页数：4
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