Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology

被引：121

作者：

Cecilia, Olvera-Montano ^{[1
]}

Jose Alberto, Castellanos-Gonzalez ^{[2
]}

Jose, Navarro-Partida ^{[3
]}

Ernesto German, Cardona-Munoz ^{[1
]}

Ana Karen, Lopez-Contreras ^{[1
]}

Luis Miguel, Roman-Pintos ^{[4
]}

Ricardo Raul, Robles-Rivera ^{[1
]}

Adolfo Daniel, Rodriguez-Carrizalez ^{[1
]}

机构：

[1] Univ Guadalajara, Hlth Sci Univ Ctr, Dept Physiol, Inst Clin & Expt Therapeut, Guadalajara, Jalisco, Mexico

[2] Mexican Inst Social Secur, Natl Occidental Med Ctr, Specialties Hosp, Dept Ophthalmol, Mexico City, DF, Mexico

[3] Tecnol Monterrey Inst, Sch Med & Hlth Sci, Campus Guadalajara, Monterrey, Mexico

[4] Univ Guadalajara, Univ Ctr Tonala, Dept Physiol, Guadalajara, Jalisco, Mexico

来源：

JOURNAL OF DIABETES RESEARCH | 2019年 / 2019卷

关键词：

ALPHA-LIPOIC ACID; SYNTHASE GENE POLYMORPHISM; RETINAL GANGLION-CELLS; GLYCATION END-PRODUCTS; NITRIC-OXIDE; VITAMIN-E; ZINC SUPPLEMENTATION; ALDOSE REDUCTASE; KAPPA-B; ANTIOXIDANT ACTIVITY;

D O I：

10.1155/2019/8562408

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In this review, we propose oxidative stress as the focus point of this complication onset.

引用

页数：21

共 50 条

[11] Pathophysiology of diabetic retinopathy
Funatsu, H
Yamashita, H
DRUG NEWS & PERSPECTIVES, 2002, 15 (10) : 633 - 639
[12] Diabetic retinopathy: hyperglycaemia, oxidative stress and beyond
Hammes, Hans-Peter
DIABETOLOGIA, 2018, 61 (01) : 29 - 38
[13] Oxidative stress, mitochondrial damage and diabetic retinopathy
Kowluru, Renu A.
Mishra, Manish
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2015, 1852 (11): : 2474 - 2483
[14] Oxidative stress and diabetic retinopathy: development and treatment
G D Calderon
O H Juarez
G E Hernandez
S M Punzo
Z D De la Cruz
Eye, 2017, 31 : 1122 - 1130
[15] Implication of oxidative stress in progression of diabetic retinopathy
Behl, Tapan
Kaur, Ishneet
Kotwani, Anita
SURVEY OF OPHTHALMOLOGY, 2016, 61 (02) : 187 - 196
[16] Oxidative stress and diabetic retinopathy: development and treatment
Calderon, G. D.
Juarez, O. H.
Hernandez, G. E.
Punzo, S. M.
De la Cruz, Z. D.
EYE, 2017, 31 (08) : 1122 - 1130
[17] Oxidative Stress and Its Regulation in Diabetic Retinopathy
Haydinger, Cameron D.
Oliver, Genevieve F.
Ashander, Liam M.
Smith, Justine R.
ANTIOXIDANTS, 2023, 12 (08)
[18] Epigenetics and Regulation of Oxidative Stress in Diabetic Retinopathy
Duraisamy, Arul J.
Mishra, Manish
Kowluru, Anjaneyulu
Kowluru, Renu A.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (12) : 4831 - 4840
[19] Role of Arginase in Oxidative Stress in Diabetic Retinopathy
Patel, C.
Zhang, W.
Baban, B.
Rojas, M.
Liou, G. I.
Caldwell, R. W.
Caldwell, R. B.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (13)
[20] Diabetic retinopathy: hyperglycaemia, oxidative stress and beyond
Hans-Peter Hammes
Diabetologia, 2018, 61 : 29 - 38

← 1 2 3 4 5 →