Mannich bases derived from 3-substituted-4-(5-nitro-2-furfurylidene) amino-1,2,4-triazole-5-thiones

被引:0
|
作者
Holla, BS [1 ]
Padmaja, MT [1 ]
Shivananda, MK [1 ]
Akberali, PM [1 ]
机构
[1] PLAMA LABS LTD,NEW MANGALORE 575011,INDIA
关键词
D O I
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of 3-substituted-4-(5-nitro-2-furfurylidene) amino-5-mercapto-1,2,4-triazoles (3) and their Mannich bases (4) were synthesized. The structure of these compounds were established on the basis of elemental analysis, H-1 NMR and mass spectral data. The newly synthesized compounds were evaluated for their antibacterial activities. The title compounds are highly active against Gram-positive bacteria at 5 mu g/ml concentration.
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页码:185 / 188
页数:4
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