Mannich bases derived from 3-substituted-4-(5-nitro-2-furfurylidene) amino-1,2,4-triazole-5-thiones

被引：0

作者：

Holla, BS ^{[1
]}

Padmaja, MT ^{[1
]}

Shivananda, MK ^{[1
]}

Akberali, PM ^{[1
]}

机构：

[1] PLAMA LABS LTD,NEW MANGALORE 575011,INDIA

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 6卷 / 03期

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D O I：

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中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 3-substituted-4-(5-nitro-2-furfurylidene) amino-5-mercapto-1,2,4-triazoles (3) and their Mannich bases (4) were synthesized. The structure of these compounds were established on the basis of elemental analysis, H-1 NMR and mass spectral data. The newly synthesized compounds were evaluated for their antibacterial activities. The title compounds are highly active against Gram-positive bacteria at 5 mu g/ml concentration.

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页码：185 / 188

页数：4

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