Rapid One-Pot Multicomponent Dioxane-HCl Complex Catalyzed Solvent-Free Synthesis of 3,4-Dihydropyrimidine-2-One Derivatives

被引：14
|
作者：
Choudhare, Tukaram S. [1 ]
Wagare, Devendra S. [2 ]
Kadam, Vijay T. [1 ]
Kharpe, Ajit A. [1 ]
Netankar, Prashant D. [1 ]
机构：
[1] Maulana Azad Coll, Dept Chem, Aurangabad 431003, India
[2] Vivekanand Arts Sardar Dalipsing Commerce & Sci C, Dept Chem, Aurangabad, India
来源：
POLYCYCLIC AROMATIC COMPOUNDS | 2022年 / 42卷 / 06期
关键词：
Dioxane-HCl complex; 3,4-dihydropyrimidine-2-one; MCRs; solvent-free; SULFUR DERIVATIVES; SILICA-GEL; BIGINELLI;
D O I：
10.1080/10406638.2021.1873808
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient one-pot multicomponent solvent-free protocol developed for the synthesis of 3,4-dihydropyrimidine-2-one derivatives from the reaction of various aromatic aldehyde, ethyl acetoacetate, urea, and dioxane-HCl as a catalyst. The main advantages of this protocol are solvent-free, atom economy, inexpensive, excellent product yield, and use of Dioxane-HCl complex as a catalyst.
引用
收藏
页码：3865 / 3873
页数：9
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