Rapid One-Pot Multicomponent Dioxane-HCl Complex Catalyzed Solvent-Free Synthesis of 3,4-Dihydropyrimidine-2-One Derivatives

被引：14

作者：

Choudhare, Tukaram S. ^{[1
]}

Wagare, Devendra S. ^{[2
]}

Kadam, Vijay T. ^{[1
]}

Kharpe, Ajit A. ^{[1
]}

Netankar, Prashant D. ^{[1
]}

机构：

[1] Maulana Azad Coll, Dept Chem, Aurangabad 431003, India

[2] Vivekanand Arts Sardar Dalipsing Commerce & Sci C, Dept Chem, Aurangabad, India

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2022年 / 42卷 / 06期

关键词：

Dioxane-HCl complex; 3,4-dihydropyrimidine-2-one; MCRs; solvent-free; SULFUR DERIVATIVES; SILICA-GEL; BIGINELLI;

D O I：

10.1080/10406638.2021.1873808

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient one-pot multicomponent solvent-free protocol developed for the synthesis of 3,4-dihydropyrimidine-2-one derivatives from the reaction of various aromatic aldehyde, ethyl acetoacetate, urea, and dioxane-HCl as a catalyst. The main advantages of this protocol are solvent-free, atom economy, inexpensive, excellent product yield, and use of Dioxane-HCl complex as a catalyst.

引用

页码：3865 / 3873

页数：9

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