Stop!: In the name of transforming growth factor-β:: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating

被引：16
|
作者：
Grimm, Sandra L. [1 ]
Rosen, Jeffrey M. [1 ]
机构：
[1] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA
来源：
BREAST CANCER RESEARCH | 2006年 / 8卷 / 04期
关键词：
D O I：
10.1186/bcr1520
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-beta signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer progression.
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Tumour necrosis factor-α accentuates transforming growth factor-β driven epithelial to mesenchymal transition (EMT) in airway epithelial cells from lung transplant recipients
    Borthwick, L. A.
    Parker, S.
    Brougham, Ka.
    Gorowiec, Mr.
    Ward, C.
    Lordan, J. L.
    Kirby, J. A.
    Corris, P. A.
    Fisher, A. J.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2008, 27 (02): : S69 - S70
  • [42] Cross-talk between Stat5b and estrogen receptor-α and -β in mammary epithelial cells
    Björnström, L
    Kilic, E
    Norman, M
    Parker, MG
    Sjöberg, M
    JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2001, 27 (01) : 93 - 106
  • [43] Antiestrogens Suppress Effects of Transforming Growth Factor-β in Breast Cancer Cells via the Signaling Axis Estrogen Receptor-α and Y-box Binding Protein-1
    Popp, Simone L.
    Joffroy, Christian
    Stope, Matthias B.
    Buck, Miriam B.
    Fritz, Peter
    Knabbe, Cornelius
    ANTICANCER RESEARCH, 2013, 33 (06) : 2473 - 2480
  • [44] Increased transforming growth factor-β2 in epidermal growth factor receptor variant III-positive glioblastoma
    Zhang, Xu
    Wu, Anhua
    Fan, Yanyan
    Wang, Yunjie
    JOURNAL OF CLINICAL NEUROSCIENCE, 2011, 18 (06) : 821 - 826
  • [45] Hepatocyte Growth Factor (HGF) Attenuates Transforming Growth Factor-β-Induced Epithelial Mesenchymal Transition in Alveolar Epithelial Cells.
    Krishnaveni, M. S.
    Zhou, B.
    Willis, B. C.
    Crandall, E. D.
    Borok, Z.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179
  • [46] EXPRESSION OF TRANSFORMING GROWTH FACTOR-ALPHA IN HUMAN MAMMARY EPITHELIAL-CELLS
    SALOMON, DS
    KIM, N
    CIARDIELLO, F
    BATES, S
    VALVERIUS, E
    DICKSON, R
    KIDWELL, WR
    CALLAHAN, R
    ALI, I
    MERLO, G
    LISCIA, D
    LIPPMAN, M
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1988, 29 : 235 - 235
  • [47] Tumor necrosis factor-α activates estrogen signaling pathways in endometrial epithelial cells via estrogen receptor α
    Gori, Ilaria
    Pellegrini, Chiara
    Staedler, Davide
    Russell, Ronan
    Jan, Caroline
    Canny, Geraldine O.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2011, 345 (1-2) : 27 - 37
  • [48] Overexpression of a kinase-deficient transforming growth factor-β type II receptor in mouse mammary stroma results in increased epithelial branching
    Joseph, H
    Gorska, AE
    Sohn, P
    Moses, HL
    Serra, R
    MOLECULAR BIOLOGY OF THE CELL, 1999, 10 (04) : 1221 - 1234
  • [49] Overaccumulation of transforming growth factor-β1 and basic fibroblast growth factor in lens epithelial cells of congenital cataract
    Xiao, Ying
    Zhao, Bojun
    Gao, Zhijuan
    Pan, Qingmin
    CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE, 2009, 44 (02): : 189 - 192
  • [50] Transforming growth factor-β during carcinogenesis:: the shift from epithelial to mesenchymal signaling
    Matsuzaki, Koichi
    Okazaki, Kazuichi
    JOURNAL OF GASTROENTEROLOGY, 2006, 41 (04) : 295 - 303
12345