Stop!: In the name of transforming growth factor-β:: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating

被引：16

作者：

Grimm, Sandra L. ^{[1
]}

Rosen, Jeffrey M. ^{[1
]}

机构：

[1] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA

来源：

BREAST CANCER RESEARCH | 2006年 / 8卷 / 04期

关键词：

D O I：

10.1186/bcr1520

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-beta signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer progression.

引用

页数：3

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