Stop!: In the name of transforming growth factor-β:: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating

被引：16
|
作者：
Grimm, Sandra L. [1 ]
Rosen, Jeffrey M. [1 ]
机构：
[1] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA
来源：
BREAST CANCER RESEARCH | 2006年 / 8卷 / 04期
关键词：
D O I：
10.1186/bcr1520
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-beta signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer progression.
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页数：3
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