Cyclocondensation reactions of nitrilimines: Synthesis of 1,2,4-triazin-6-ones and 1,2,4,5-tetrazines

被引：0
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作者：
Awadallah, AM [1 ]
Ferwanah, ARS
El-Sawi, EA
Dalloul, HM
机构：
[1] Islam Univ Gaza, Fac Sci, Dept Chem, Gaza, Israel
[2] Al Azhar Univ Gaza, Fac Sci, Dept Chem, Gaza, Israel
[3] Ain Shams Univ, Univ Coll Women, Dept Chem, Cairo, Egypt
来源：
HETEROCYCLIC COMMUNICATIONS | 2002年 / 8卷 / 04期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Nitrilimines 2a-c react with alpha-amino esters 3-7 to afford 1,2,4-triazin-6-ones 9-13. The reaction of nitrilimines with the aza analogues of amnio esters 1-ethoxycarbonyl-1-methylhydrazine 8 gives the acyclic adducts 14a-c which undergo thermal oxidative cyclization at CH3 to give the unexpected 1,2,4,5-tetrazines 15a-c rather than the expected tetrazinones 16a-c.
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页码：369 / 374
页数：6
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