A new sesquiterpene lactone glucoside with inhibitory effect on K562 cells from Ixeris sonchifolia (Bge) Hance

被引:17
|
作者
He, W. -F.
Xu, B. -B.
Pan, J. -C.
Lu, J. -C.
Song, S. -J.
Xu, S. -X. [1 ]
机构
[1] Wenzhou Med Coll, Sch Pharm, Wenzhou 325035, Peoples R China
[2] Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Peoples R China
关键词
Ixeris sonchifolia; compositae; Ixerin Z(A); K-562; cells;
D O I
10.1080/10286020500532140
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new minor sesquiterpene lactone glucoside, ixerin Z(A) ( 1), together with 16 known compounds, were isolated from the whole plants of Ixeris sonchifolia (Bge) Hance. The structure of 1 was elucidated as 1(10),3,11(13)-guaiatriene-12,6-olide-2-one-3-O-[6 '-(p-metheoxyphenylacetyl)]-beta-glucopyranoside on the basis of spectroscopic and chemical evidence. Compound 1 exhibited an inhibitory effect on K-562 cells.
引用
收藏
页码:481 / 484
页数:4
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