Bone marrow transplant for a girl with bone marrow failure and cerebral palsy

被引：1

作者：

Kodama, Yuichi ^{[1
]}

Okamoto, Yasuhiro ^{[1
]}

Shinkoda, Yuichi ^{[1
]}

Tanabe, Takayuki ^{[1
]}

Nishikawa, Takuro ^{[1
]}

Yamaki, Yuni ^{[1
]}

Kurauchi, Koichiro ^{[1
]}

Kawano, Yoshifumi ^{[1
]}

机构：

[1] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Pediat, Kagoshima 8908520, Japan

来源：

PEDIATRICS INTERNATIONAL | 2014年 / 56卷 / 03期

基金：

日本学术振兴会;

关键词：

bone marrow transplantation; cerebral palsy; congenital bone marrow failure; mental retardation; CELL TRANSPLANTATION; APLASTIC-ANEMIA; CHILDREN; BRAIN;

D O I：

10.1111/ped.12297

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Bone marrow transplantation (BMT) has been used with increasing frequency to treat congenital bone marrow failure syndrome (CBMFs) successfully. Decision to perform BMT, however, is difficult in the case of comorbidity because of regimen-related toxicities. We describe here a child with CBMFs, severe cerebral palsy (CP) at Gross Motor Function Classification System level V and mental retardation (MR) who was transfusion dependent despite various medications. She underwent BMT from an HLA-1 locus-mismatched unrelated donor. Although engraftment was successful, no neurological improvement was seen 5 years after BMT. While CBMFs patients who have CP and MR could undergo transplantation safely, they may not benefit neurologically from BMT.

引用

页码：424 / 426

页数：3

共 50 条

[21] Correction of bone marrow failure in dyskeratosis congenita by bone marrow transplantation
A Ghavamzadeh
K Alimoghadam
P Nasseri
M Jahani
A Khodabandeh
G Ghahremani
[J]. Bone Marrow Transplantation, 1999, 23 : 299 - 301
[22] BONE-MARROW IN BONE VERSUS BONE-MARROW CELL-SUSPENSION TRANSPLANT
OLSZEWSKI, WL
LUKOMSKA, B
DURLIC, M
ZIEMBINSKI, A
[J]. TRANSPLANTATION PROCEEDINGS, 1992, 24 (06) : 3002 - 3003
[23] Mosaic isochromosome Xp in a girl with short stature and bone marrow failure
Morerio, C.
Tavella, E.
Casalaro, A.
Cappelli, E.
Dufour, C.
Panarello, C.
Tassano, E.
[J]. CHROMOSOME RESEARCH, 2009, 17 : 121 - 121
[24] MOSAIC ISOCHROMOSOME XP IN A GIRL WITH SHORT STATURE AND BONE MARROW FAILURE
Morerio, C.
Tavella, E.
Casalaro, A.
Cappelli, E.
Dufour, C.
Panarello, C.
Tassano, E.
[J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 491 - 491
[25] Targeting Bone Marrow Niche Macrophages: The Novel Frontier in Bone Marrow Transplant
Vinchi, Francesca
[J]. HEMASPHERE, 2018, 2 (05):
[26] Risk Factors for Donor-Type Aplasia after Bone Marrow Transplant in Children with Acquired Bone Marrow Failure
Hama, Asahito
Muramatsu, Hideki
Narita, Atsushi
Kitazawa, Hironobu
Hamada, Motoharu
Kataoka, Shinsuke
Murakami, Norihiro
Ichikawa, Daisuke
Taniguchi, Rieko
Kojima, Daiei
Suzuki, Kyogo
Nishikawa, Eri
Okuno, Yusuke
Kawashima, Nozomu
Nishio, Nobuhiro
Ito, Masafumi
Kojima, Seiji
Takahashi, Yoshiyuki
[J]. BLOOD, 2017, 130
[27] Hypocupremia and bone marrow failure
Haddad, A. S.
Subbiah, V.
Lichtin, A. E.
Theil, K. S.
Maciejewski, J. P.
[J]. HAEMATOLOGICA, 2007, 93 (01) : E1 - E5
[28] Congenital bone marrow failure
Gazda, H
[J]. INTERNATIONAL JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY, 1999, 6 (02): : 131 - 145
[29] The pathology of bone marrow failure
Leguit, Roos J.
van den Tweel, Jan G.
[J]. HISTOPATHOLOGY, 2010, 57 (05) : 655 - 670
[30] VERY EARLY BONE MARROW TRANSPLANT IN A GIRL WITH I-CELL DISEASE
v Arnim-Baas, A.
Kuehl, J.
Buerger, F.
Hennermann, J. B.
[J]. JOURNAL OF INHERITED METABOLIC DISEASE, 2005, 28 : 178 - 178

← 1 2 3 4 5 →