Convenient synthesis of some 2-substituted 4(3H)-quinazolinone derivatives

被引：21

作者：

Philipova, I. ^{[1
]}

Dobrikov, G. ^{[1
]}

Krumova, K. ^{[1
]}

Kaneti, J. ^{[1
]}

机构：

[1] Bulgarian Acad Sci, Ctr Phytochem, Inst Organ Chem, BU-1113 Sofia, Bulgaria

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 43卷 / 04期

关键词：

D O I：

10.1002/jhet.5570430436

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 2-substituted-4(3H)-quinazolinones 13-20 has been synthesized in good yields using the reaction of double lithiated 2-methylquinazolinone-4 with a variety of aromatic aldehydes. They have been easily transformed in high yields into the corresponding 2-substituted conjugated derivatives 21-28 bearing terminal aryl groups by F3CCCOH mediated dehydration.

引用

页码：1057 / 1063

页数：7

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