Combinatorial therapies for rescuing myotonic dystrophy type 1 skeletal muscle defects

被引：4

作者：

Ravel-Chapuis, Aymeric ^{[1
,2
]}

Jasmin, Bernard J. ^{[1
,2
]}

机构：

[1] Univ Ottawa, Fac Med, Dept Cellular & Mol Med, Ottawa, ON, Canada

[2] Univ Ottawa, Fac Med, Er Poulin Ctr Neuromuscular Dis, Ottawa, ON, Canada

来源：

TRENDS IN MOLECULAR MEDICINE | 2022年 / 28卷 / 06期

关键词：

D O I：

10.1016/j.molmed.2022.04.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Myotonic dystrophy type 1 (DM1) is a multisystemic disorder for which there is no cure. In recent years, progress has been made in defining disease mechanisms and in developing novel therapies, especially for skeletal muscle defects. Here, we highlight the potential of activating AMP-activated protein kinase (AMPK) with different approaches in combinatorial therapies.

引用

页码：439 / 442

页数：4

共 50 条

[21] Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2
Mankodi, A
Teng-Umnuay, P
Krym, M
Henderson, D
Swanson, M
Thornton, CA
ANNALS OF NEUROLOGY, 2003, 54 (06) : 760 - 768
[22] A Case of Myotonic Dystrophy Type I With Rimmed Vacuoles in Skeletal Muscle Pathology
Ban, Rui
Zhang, Yutong
Li, Ke
Shi, Qiang
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2021, 27 (8S) : S771 - S772
[23] Skeletal muscle involvement in myotonic dystrophy type 2. A comparative muscle ultrasound study
Tieleman, A. A.
Vinke, A.
van Alfen, N.
van Dijk, J. P.
Pillen, S.
van Engelen, B. G. M.
NEUROMUSCULAR DISORDERS, 2012, 22 (06) : 492 - 499
[24] Resistance Exercise Training Rescues Mitochondrial Dysfunction in Skeletal Muscle of Patients with Myotonic Dystrophy Type 1
Di Leo, Valeria
Lawless, Conor
Roussel, Marie-Pier
Gomes, Tiago B.
Gorman, Grainne S.
Russell, Oliver M.
Tuppen, Helen A. L.
Duchesne, Elise
Vincent, Amy E.
JOURNAL OF NEUROMUSCULAR DISEASES, 2023, 10 (06) : 1111 - 1126
[25] Splicing in two skeletal muscle transcripts correlates with clinical phenotype in myotonic dystrophy type 1 patients
Sedehizadeh, Saam
Wojciechowska, Marzena
Ketley, Ami
Brook, J. David
Maddison, Paul
JOURNAL OF NEUROLOGY, 2022, 269 (05) : 2784 - 2787
[26] Electromechanical delay components during skeletal muscle contraction and relaxation in patients with myotonic dystrophy type 1
Esposito, Fabio
Ce, Emiliano
Rampichini, Susanna
Limonta, Eloisa
Venturelli, Massimo
Monti, Elena
Bet, Luciano
Fossati, Barbara
Meola, Giovanni
NEUROMUSCULAR DISORDERS, 2016, 26 (01) : 60 - 72
[27] Training program-induced skeletal muscle adaptations in two men with myotonic dystrophy type 1
Marie-Pier Roussel
Marika Morin
Mélina Girardin
Anne-Marie Fortin
Mario Leone
Jean Mathieu
Cynthia Gagnon
Elise Duchesne
BMC Research Notes, 12
[28] Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle
Fernandez-Garibay, Xiomara
Ortega, Maria A.
Cerro-Herreros, Estefania
Comelles, Jordi
Martinez, Elena
Artero, Ruben
Fernandez-Costa, Juan M.
Ramon-Azcon, Javier
BIOFABRICATION, 2021, 13 (03)
[29] BIOENGINEERED IN VITRO 3D MODEL OF MYOTONIC DYSTROPHY TYPE 1 HUMAN SKELETAL MUSCLE
Fernandez-Garibay, Xiomara
Ortega, Maria A.
Cerro-Herreros, Estefania
Comelles, Jordi
Martinez, Elena
Artero, Ruben
Fernandez-Costa, Juan M.
Ramon-Azcon, Javier
TISSUE ENGINEERING PART A, 2022, 28 : S591 - S591
[30] Splicing in two skeletal muscle transcripts correlates with clinical phenotype in myotonic dystrophy type 1 patients
Saam Sedehizadeh
Marzena Wojciechowska
Ami Ketley
J. David Brook
Paul Maddison
Journal of Neurology, 2022, 269 : 2784 - 2787

← 1 2 3 4 5 →