Synthesis of α-aminophosphonates by the Kabachnik-Fields reaction

被引:21
|
作者
Sravya, G. [1 ]
Balakrishna, A. [2 ]
Zyryanov, Grigory, V [1 ,3 ]
Mohan, G. [4 ,5 ]
Reddy, C. Suresh [4 ]
Reddy, N. Bakthavatchala [1 ]
机构
[1] Ural Fed Univ, Chem Engn Inst, Ekaterinburg 620002, Russia
[2] Rajeev Gandhi Mem Coll Engn & Technol Autonomous, Nandyal, Andhra Pradesh, India
[3] Russian Acad Sci, I Ya Postovskiy Inst Organ Synth, Ural Div, Ekaterinburg, Russia
[4] Sri Venkateswara Univ, Dept Chem, Tirupati, Andhra Pradesh, India
[5] Sri Venkateswara Univ, DST PURSE Ctr, Tirupati, Andhra Pradesh, India
关键词
Synthesis; α -aminophosphonates; Kabachnik-Fields reaction; ONE-POT SYNTHESIS; LITHIUM PERCHLORATE/DIETHYL ETHER; AMINO-PHOSPHONATES; SOLVENT-FREE; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; 3-COMPONENT SYNTHESIS; CARBONYL-COMPOUNDS; FACILE SYNTHESIS; CATALYST-FREE;
D O I
10.1080/10426507.2020.1854258
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The review discusses recent achievements in the development of more ecofriendly and economically viable processes for the synthesis of biologically potent alpha-aminophosphonates via Kabachnik-Fields reaction by three-component coupling of carbonyl, amine and hydrophosphoryl compounds. These alpha-aminophosphonates exhibited promising antioxidant, antimicrobial and anticancer activity. Some recent developments on the synthesis of biologically active alpha-aminophosphonates in the presence of various catalysts, in catalytic solvent medium, in catalyst-free solvent medium, under solvent-free conditions, and reactions in solution are discussed. Miscellaneous reactions are also included.
引用
收藏
页码:353 / 381
页数:29
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