Synthesis of 5-aryl-4-aroyl-3-hydroxy-1-(4-guanidylsulfonylphenyl)-3-pyrrolin-2-ones

被引：3
|
作者：
Gein, V. L. [1 ]
Kovtonogova, I. V. [1 ]
Bobrovskaya, O. V. [1 ]
Vakhrin, M. I. [1 ]
机构：
[1] Perm State Pharmaceut Acad, Perm 614990, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2014年 / 84卷 / 02期
关键词：
General Chemistry; Schiff Base; Glacial Acetic Acid; Aromatic Aldehyde; Fluorobenzaldehyde;
D O I：
10.1134/S1070363214020170
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three-component reaction of methyl aroylpyruvate with aromatic aldehyde and 4-aminobenzenesulfonylguanidine resulted in 5-aryl-4-aroyl-3-hydroxy-1-(4-guanidylsulfonylphenyl)-3-pyrrolin-2-ones.
引用
收藏
页码：264 / 267
页数：4
相关论文
共 50 条
  • [41] Synthesis and biological activity of 5-aryl-4-acyl-3-hydroxy-1- morpholinoalkyl-3-pyrrolin-2-ones
    Gein V.L.
    Yushkov V.V.
    Kasimova N.N.
    Voronina E.V.
    Rakshina N.S.
    Vasil'eva M.Yu.
    Pharmaceutical Chemistry Journal, 2007, 41 (5) : 256 - 263
  • [42] Synthesis and Antibacterial Activity of 1-(4-Aminosulfonylphenyl)-5-aryl-4-acyl-3-hydroxy-3-pyrrolin-2-ones
    V. L. Gein
    T. F. Odegova
    K. A. Tkachenko
    O. V. Bobrovskaya
    M. I. Vakhrin
    Pharmaceutical Chemistry Journal, 2013, 47 : 371 - 373
  • [43] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 1-(4-HYDROXYPHENYL)-4-ACYL-5-ARYL-3-HYDROXY-3-PYRROLIN-2-ONES
    Gein, V. L.
    Armisheva, M. N.
    Rassudikhina, N. A.
    Vakhrin, M. I.
    Voronina, E. V.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2011, 45 (03) : 162 - 164
  • [44] Synthesis and Some Transformations of 5-Aryl-4-(4-halogenaroyl)-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones
    Gein, V. L.
    Pastukhova, E. V.
    Korol, A. N.
    Dozmorova, N. V.
    Voronina, E. V.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2020, 90 (12) : 2225 - 2229
  • [45] Synthesis and pharmacological activity of 1-substituted 5-aryl-4-acyl-3-hydroxy-3-pyrrolin-2-ones
    Gein V.L.
    Gein L.F.
    Porseva N.Yu.
    Voronina É.V.
    Vakhrin M.I.
    Potemkin K.D.
    Kolla V.E.
    Drovosekova L.P.
    Milyutin A.V.
    Shchuklina N.S.
    Veikhman G.A.
    Pharmaceutical Chemistry Journal, 1998, 32 (9) : 477 - 479
  • [46] Synthesis and antibacterial activity of 1-alkoxyalkyl-5-aryl-4-acyl-3- hydroxy-3-pyrrolin-2-ones
    Gein V.L.
    Mihalev V.A.
    Kasimova N.N.
    Voronina E.V.
    Vakhrin M.I.
    Babushkina E.B.
    Pharmaceutical Chemistry Journal, 2007, 41 (4) : 208 - 210
  • [47] Synthesis and Some Transformations of 5-Aryl-4-(4-halogenaroyl)-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones
    V. L. Gein
    E. V. Pastukhova
    A. N. Korol
    N. V. Dozmorova
    E. V. Voronina
    Russian Journal of General Chemistry, 2020, 90 : 2225 - 2229
  • [48] SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 1-(4-AMINOSULFONYLPHENYL)-5-ARYL-4-ACYL-3-HYDROXY-3-PYRROLIN-2-ONES
    Gein, V. L.
    Odegova, T. F.
    Tkachenko, K. A.
    Bobrovskaya, O. V.
    Vakhrin, M. I.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2013, 47 (07) : 371 - 373
  • [49] Synthesis and Analgesic and Anti-Inflammatoryactivity of 5-aryl-4-acetyl-3-hydroxy-1-carboxymethyl-3-pyrrolin-2-ones
    V. L. Gein
    E. V. Pastukhova
    S. V. Chashchina
    Pharmaceutical Chemistry Journal, 2022, 56 : 321 - 324
  • [50] Synthesis and Analgesic and Anti-Inflammatoryactivity of 5-aryl-4-acetyl-3-hydroxy-1-carboxymethyl-3-pyrrolin-2-ones
    Gein, V. L.
    Pastukhova, E., V
    Chashchina, S., V
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2022, 56 (03) : 321 - 324
12345