Design and Analysis of a Laminar Diffusion-Based Micromixer with Microfluidic Chip

被引:0
|
作者
Ulkir, Osman [1 ]
Girit, Oguz [2 ]
Ertugrul, Ishak [3 ]
机构
[1] Mus Alparslan Univ, Dept Elect & Automat, TR-49100 Mus, Turkey
[2] Marmara Univ, Dept Machine Engn, TR-34100 Istanbul, Turkey
[3] Mus Alparslan Univ, Dept Mechatron, TR-49100 Mus, Turkey
关键词
NUMERICAL-SIMULATION; HIGH-THROUGHPUT; SYSTEM; MIXER;
D O I
10.1155/2021/6684068
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
This study aims to perform optimizatione to achieve the best diffusion control between the channels by designing and analysing a microfluidic-based micromixer. The design and analysis of the micromixer were made with the COMSOL Multiphysics program. Some input and output parameters must be defined for diffusion control of the micromixer. Among these parameters, inputs are the diffusion coefficient and inlet flow rate, while outputs are velocity, pressure, and concentration. Each input parameter in the microfluidic chip affects the output of the system. To make the diffusion control in the most optimum way, the data were obtained by making much analysis. The data obtained from this program was also provided with the Fuzzy Logic method to optimize the microfluidic chip. The diffusion coefficient value (5E-11 m(2)/s) should be given to the channels to achieve the optimum diffusion between the micromixer channels, if the inlet flow rate value (15E-15 m(3)/s) is the output value of the system, the velocity is 0.09 mm/s. The pressure is 2 Pa, and the concentration is 0.45 mol/m(3). These values are the optimum values obtained from the analysis without damaging the liquid's microfluidic channels supplied to the micromixer's inlet.
引用
收藏
页数:10
相关论文
共 50 条
  • [1] Design and Analysis of a Laminar Diffusion-Based Micromixer with Microfluidic Chip
    Ulkir, Osman
    Girit, Oguz
    Ertugrul, Ishak
    [J]. Journal of Nanomaterials, 2021, 2021
  • [2] Diffusion-based analysis of molecular interactions in microfluidic devices
    Hatch, A
    Garcia, E
    Yager, P
    [J]. PROCEEDINGS OF THE IEEE, 2004, 92 (01) : 126 - 139
  • [3] A parallel diffusion-based microfluidic device for bacterial chemotaxis analysis
    Si, Guangwei
    Yang, Wei
    Bi, Shuangyu
    Luo, Chunxiong
    Ouyang, Qi
    [J]. LAB ON A CHIP, 2012, 12 (07) : 1389 - 1394
  • [4] Optimal Design of Microfluidic Platforms for Diffusion-Based PCR for "One-Pot" Analysis of Cells
    Crow, Jordan
    Achenie, Luke E. K.
    Lu, Chang
    Ma, Sai
    Loufakis, Despina Nelie
    Cao, Zhenning
    Chang, Yiwen
    [J]. 12TH INTERNATIONAL SYMPOSIUM ON PROCESS SYSTEMS ENGINEERING (PSE) AND 25TH EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING (ESCAPE), PT B, 2015, 37 : 1199 - 1204
  • [5] Cultivation of yeast in diffusion-based microfluidic device
    Oliveira, A. F.
    Pelegati, V. B.
    Carvalho, H. F.
    Cesar, C. L.
    Bastos, R. G.
    de la Torre, L. G.
    [J]. BIOCHEMICAL ENGINEERING JOURNAL, 2016, 105 : 288 - 295
  • [6] Microfluidics - Microfluidic diffusion-based separation and detection
    Weigl, BH
    Yager, P
    [J]. SCIENCE, 1999, 283 (5400) : 346 - 347
  • [7] Diffusion-based microfluidic PCR for "one-pot" analysis of cells
    Ma, Sai
    Loufakis, Despina Nelie
    Cao, Zhenning
    Chang, Yiwen
    Achenie, Luke E. K.
    Lu, Chang
    [J]. LAB ON A CHIP, 2014, 14 (16) : 2905 - 2909
  • [8] A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis
    Wang, Wei
    Zeng, Zhi
    Xu, Wei
    Wu, Wenming
    Liang, Wenfeng
    Zhou, Jia
    [J]. MICROMACHINES, 2018, 9 (12):
  • [9] Analysis of raw biofluids by mass spectrometry using microfluidic diffusion-based separation
    Heinemann, Joshua
    Noon, Brigit
    Willems, Daniel
    Budeski, Katherine
    Bothner, Brian
    [J]. ANALYTICAL METHODS, 2017, 9 (03) : 385 - 392
  • [10] Modelling and Analysis of Microfluidic Micromixer for Lab-On-a-Chip(LoC) Application
    Saikat, Chakraborty
    Sharath, M.
    Srujana, M.
    Narayan, K.
    Kumar, Pattnaik Prasant
    [J]. 2015 ANNUAL IEEE INDIA CONFERENCE (INDICON), 2015,