Hierarchically aligned porous scaffold by ice-segregation-induced self-assembly and thermally triggered electrostatic self-assembly of oppositely charged thermosensitive microgels

被引:20
|
作者
Yao, Xiang [2 ]
Yao, Hongwei [1 ]
Li, Yuanting [2 ]
机构
[1] Qingdao Univ, Dept Polymer Sci & Engn, Qingdao 266071, Peoples R China
[2] Tsinghua Univ, Dept Chem Engn, Beijing 100084, Peoples R China
关键词
NANOPARTICLES;
D O I
10.1039/b909059b
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
We present a new method for the fabrication of a 3-dimensional hierarchical aligned porous scaffold by a combined ice-segregation-induced self-assembly and thermally triggered electrostatic self-assembly method. The oppositely charged thermosensitive microgels were used as the building blocks of the scaffold. The porous structure can be controlled by adjusting both the directional freezing conditions and microgel components. The scaffold thus prepared may survive in a physiological environment (37 degrees C in water) and has great potential in biomedical applications such as tissue engineering.
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页码:6516 / 6520
页数:5
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