Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach

被引:28
|
作者
Chen, Huiling [1 ,3 ]
Yang, Bo [2 ,3 ]
Liu, Dayou [2 ,3 ]
Liu, Wenbin [1 ]
Liu, Yanlong [4 ]
Zhang, Xiuhua [5 ]
Hu, Lufeng [5 ]
机构
[1] Wenzhou Univ, Coll Phys & Elect Informat Engn, Wenzhou, Peoples R China
[2] Jilin Univ, Coll Comp Sci & Technol, Changchun 130023, Peoples R China
[3] Jilin Univ, Minist Educ, Key Lab Symbol Computat & Knowledge Engn, Changchun 130023, Peoples R China
[4] Wenzhou Med Univ, Coll Pharmaceut Sci, Wenzhou, Peoples R China
[5] Wenzhou Med Univ, Affiliated Hosp 1, Dept Pharmaceut, Wenzhou, Peoples R China
来源
PLOS ONE | 2015年 / 10卷 / 11期
基金
中国国家自然科学基金;
关键词
BODY-MASS INDEX; FEEDFORWARD NETWORKS; LOGISTIC-REGRESSION; GLUCOSE-TOLERANCE; OBESITY; CLASSIFICATION; DISEASE; NUMBER; RISK;
D O I
10.1371/journal.pone.0143003
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The number of the overweight people continues to rise across the world. Studies have shown that being overweight can increase health risks, such as high blood pressure, diabetes mellitus, coronary heart disease, and certain forms of cancer. Therefore, identifying the overweight status in people is critical to prevent and decrease health risks. This study explores a new technique that uses blood and biochemical measurements to recognize the overweight condition. A new machine learning technique, an extreme learning machine, was developed to accurately detect the overweight status from a pool of 225 overweight and 251 healthy subjects. The group included 179 males and 297 females. The detection method was rigorously evaluated against the real-life dataset for accuracy, sensitivity, specificity, and AUC (area under the receiver operating characteristic (ROC) curve) criterion. Additionally, the feature selection was investigated to identify correlating factors for the overweight status. The results demonstrate that there are significant differences in blood and biochemical indexes between healthy and overweight people (p-value < 0.01). According to the feature selection, the most important correlated indexes are creatinine, hemoglobin, hematokrit, uric Acid, red blood cells, high density lipoprotein, alanine transaminase, triglyceride, and. gamma-glutamyl transpeptidase. These are consistent with the results of Spearman test analysis. The proposed method holds promise as a new, accurate method for identifying the overweight status in subjects.
引用
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页数:18
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