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Unraveling the genetics of autoimmune disease
被引:3
|作者:
Vyse, Timothy J.
[1
]
机构:
[1] Univ London Imperial Coll Sci Technol & Med, Sect Mol Genet & Rheumatol, Fac Med, London W12 0NN, England
关键词:
GENOME-WIDE ASSOCIATION;
D O I:
10.1038/nrrheum.2009.42
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
The ability to conduct genetic association studies on a genome-wide scale has revolutionized approaches to reveal the genetic basis of autoimmune diseases. a comparison by Zhernakova and colleagues of the known susceptibility genes in 11 immune-related diseases reveals evidence for shared gene effects and common pathogenetic mechanisms.
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页码:187 / 188
页数:3
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