Whole-Genome Sequencing of the Mycobacterium tuberculosis Manila Sublineage Results in Less Clustering and Better Resolution than Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat (MIRU-VNTR) Typing and Spoligotyping

被引：26

作者：

Jamieson, F. B. ^{[1
,2
]}

Teatero, S. ^{[1
]}

Guthrie, J. L. ^{[1
]}

Neemuchwala, A. ^{[1
]}

Fittipaldi, N. ^{[1
,2
]}

Mehaffy, C. ^{[1
,2
]}

机构：

[1] Publ Hlth Ontario, Toronto, ON, Canada

[2] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2014年 / 52卷 / 10期

关键词：

NUCLEOTIDE POLYMORPHISMS; EPIDEMIOLOGY; OUTBREAK; STRAINS;

D O I：

10.1128/JCM.01726-14

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Mycobacterium tuberculosis isolates of the Manila sublineage are genetically homogeneous. In this study, we used whole-genome sequencing (WGS) to type a collection of 36 M. tuberculosis isolates of the Manila family. WGS enabled the subtyping of these 36 isolates into at least 10 distinct clusters. Our results indicate that WGS is a powerful approach to determining the relatedness of Manila family M. tuberculosis isolates.

引用

页码：3795 / 3798

页数：4

共 42 条

[41] Whole-Genome Sequencing Exhibits Better Diagnostic Performance than Variable-Number Tandem Repeats for Identifying Mixed Infections of Mycobacterium tuberculosis
Chen, Yiwang
Jiang, Qi
Liu, Qingyun
Gan, Mingyu
Takiff, Howard E.
Gao, Qian
MICROBIOLOGY SPECTRUM, 2023, 11 (03)
[42] High genetic diversity among Mycobacterium avium subsp paratuberculosis strains from German cattle herds shown by combination of IS900 restriction fragment length polymorphism analysis and mycobacterial interspersed repetitive unit-variable-number tandem-repeat typing
Moebius, Petra
Luyven, Gabriele
Hotzel, Helmut
Koehler, Heike
JOURNAL OF CLINICAL MICROBIOLOGY, 2008, 46 (03) : 972 - 981

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