Valproate-associated dysmyelopoiesis in elderly patients

被引：14

作者：

So, CC ^{[1
]}

Wong, KF ^{[1
]}

机构：

[1] Queen Elizabeth Hosp, Dept Pathol, Kowloon, Hong Kong, Peoples R China

来源：

AMERICAN JOURNAL OF CLINICAL PATHOLOGY | 2002年 / 118卷 / 02期

关键词：

sodium valproate; hematologic toxicity; dysmyelopoiesis; myelodysplasia; elderly;

D O I：

10.1309/4TEF-LVGX-WEQ9-R8W8

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Sodium valproate is widely prescribed for patients with epilepsy and psychiatric disorders. Hematologic toxic effects have been largely described in pediatric patients, and dysmyelopoiesis is reported rarely. We describe 21 elderly patients with valproate-associated dysmyelopoiesis and postulate that this particular side effect may be much more common than currently recognized. A correct diagnosis is important for acute patient management and for prognostication.

引用

页码：225 / 228

页数：4

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