Uromodulin, kidney function, cardiovascular disease, and mortality

被引：21

作者：

Devuyst, Olivier ^{[1
]}

Bochud, Murielle ^{[2
]}

机构：

[1] Univ Zurich, Inst Physiol, CH-8057 Zurich, Switzerland

[2] CHU Vaudois, Univ Lausanne Hosp, Univ Inst Social & Prevent Med, CH-1011 Lausanne, Switzerland

来源：

KIDNEY INTERNATIONAL | 2015年 / 88卷 / 05期

关键词：

ASSOCIATE; VARIANTS;

D O I：

10.1038/ki.2015.267

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Uromodulin (Tamm-Horsfall protein) is exclusively produced by the kidney and is the most abundant protein excreted in normal urine. The level of uromodulin in urine could represent a useful biomarker for renal tubular function. The study of Garimella et al. adds elements into the debate, by suggesting that, in elderly adults, low urinary uromodulin concentrations in spot urine identify people at risk of progressive kidney disease and mortality above and beyond established markers of kidney disease.

引用

页码：944 / 946

页数：3

共 50 条

[31] EVALUATION OF UROMODULIN AS NEW SERUM MARKER FOR RENAL FUNCTION AND THE INCIDENCE OF CHRONIC KIDNEY DISEASE
Leiherer, Andreas
Muendlein, Axel
Saely, Christoph
Rein, Philipp
Vonbank, Alexander
Kinz, Elena
Brandtner, Eva-Maria
Fraunberger, Peter
Schwerzler, Peter
Mader, Arthur
Drexel, Heinz
ATHEROSCLEROSIS, 2017, 263 : E196 - E196
[32] Kidney disease as a risk factor for recurrent cardiovascular disease and mortality
Weiner, DE
Tighiouart, H
Stark, PC
Amin, MG
MacLeod, B
Griffith, JL
Salem, DN
Levey, AS
Sarnak, MJ
AMERICAN JOURNAL OF KIDNEY DISEASES, 2004, 44 (02) : 198 - 206
[33] Serum and Urine Uromodulin, Kidney Volume, and Function in Living Kidney Donors
Erdut, Arda
Jabrayilov, Jabrayil
Onal, Ceren
Kibar, Muge Uzerk
Hazirolan, Tuncay
Bozaci, Ali C.
Yildirim, Tolga
Altun, Bulent
Aki, Fazil T.
Arici, Mustafa
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022, 33 (11): : 543 - 543
[34] Uromodulin and microRNAs in Kidney Transplantation-Association with Kidney Graft Function
Borstnar, Spela
Veceric-Haler, Zeljka
Bostjancic, Emanuela
Tkalec, Ziva Pipan
Kovac, Damjan
Lindic, Jelka
Kojc, Nika
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (16) : 1 - 11
[35] Kidney function as a predictor for long-term mortality in patients with stable chronic cardiovascular disease
Ishikawa, Y
Nishikimi, T
Horio, T
Ishimura, K
Nagaya, N
Yoshihara, F
Koshikawa, S
Mori, Y
Kawano, Y
Matsuoka, H
JOURNAL OF CARDIAC FAILURE, 2005, 11 (09) : S308 - S308
[36] Slope of Kidney Function and Its Association with Longitudinal Mortality and Cardiovascular Disease among Individuals with CKD
Orlandi, Paula F.
Xie, Dawei
Yang, Wei
Cohen, Jordana B.
Deo, Rajat
Ricardo, Ana C.
Schrauben, Sarah
Wang, Xue
Hamm, L. Lee
He, Jiang
Sondheimer, James H.
Kallem, Krishna
Townsend, Raymond
Raj, Dominic
Parsa, Afshin
Anderson, Amanda H.
Feldman, Harold, I
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2020, 31 (12): : 2912 - 2923
[37] Serial decline of kidney function predicts total mortality and cardiovascular events in coronary artery disease
Rein, P.
Saely, C.
Vonbank, A.
Drexel, H.
WIENER KLINISCHE WOCHENSCHRIFT, 2013, 125 (17-18) : 568 - 568
[38] Influence of Lung Function and Cardiovascular Disease on Mortality
Sekitoleko, I.
Robertson, N.
Anonubi, C.
Jackson, P. D.
Padalker, R.
Herrera, P.
Nyirenda, M.
Webb, E.
Punjabi, N. M.
Siddharthan, T.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2022, 205
[39] Chronic kidney disease as cause of cardiovascular morbidity and mortality
Vanholder, R
Massy, Z
Argiles, A
Spasovski, G
Verbeke, F
Lameire, N
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2005, 20 (06) : 1048 - 1056
[40] Cardiovascular Determinants of Mortality in Advanced Chronic Kidney Disease
Lankinen, Roosa
Hakamaki, Markus
Metsarinne, Kaj
Koivuviita, Niina S.
Parkk, Jussi P.
Hellman, Tapio
Kartiosuo, Noora
Raitakari, Olli T.
Jarvisalo, Mikko J.
AMERICAN JOURNAL OF NEPHROLOGY, 2020, 51 (09) : 726 - 735

← 1 2 3 4 5 →