Phase-Separation-Induced Formation of Janus Droplets Based on Aqueous Two-Phase Systems

被引：46
|
作者：
Yuan, Hao [1 ,2 ]
Ma, Qingming [1 ,2 ]
Song, Yang [1 ,2 ]
Tang, Matthew Y. H. [1 ,2 ]
Chan, Yau Kei [1 ,2 ]
Shum, Ho Cheung [1 ,2 ]
机构：
[1] Univ Hong Kong, Dept Mech Engn, Pokfulam Rd, Hong Kong, Hong Kong, Peoples R China
[2] HKU SIRI, Shenzhen 518000, Peoples R China
来源：
MACROMOLECULAR CHEMISTRY AND PHYSICS | 2017年 / 218卷 / 02期
基金：
中国国家自然科学基金;
关键词：
aqueous two-phase system; bioactivity preservation; droplet microfluidics; phase separation; ORDER MULTIPLE EMULSIONS; POLYMER BLENDS; MICROFLUIDIC FABRICATION; TRANSGENIC MICE; PARTICLES; NANOPARTICLES; MICROPARTICLES; TUMORS;
D O I：
10.1002/macp.201600422
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
In this study, Janus droplets are fabricated by inducing phase separation of single-phase droplets made up of an aqueous two-phase system (ATPS). The resultant Janus droplets are highly monodisperse in structures and internal morphologies. Due to the affinity partitioning properties of ATPS, encapsulated ingredients can automatically partition into different compartments of the resultant Janus droplets. The use of biocompatible and cytocompatible ATPS also enables the encapsulation of enzymes and cells in the resultant droplets with their activity preserved at a relatively high level.
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页数：8
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