Solid-phase organic chemistry:: Synthesis of 2β-(heterocyclylthiomethyl)penam derivatives on solid support

被引：4

作者：

Delpiccolo, CML ^{[1
]}

Mata, EG ^{[1
]}

机构：

[1] Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, CONICET, Inst Quim Organ Sintesis, RA-2000 Rosario, Santa Fe, Argentina

来源：

MOLECULES | 2000年 / 5卷 / 03期

关键词：

D O I：

10.3390/50300537

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of 2 beta-(heterocyclylthiomethyl)penam derivatives on solid support has been developed. Compounds are obtained in good to high yields (based on loading of the original resin). The key step is the solid-phase double rearrangement of the corresponding penicillin sulfoxide.

引用

页码：537 / 538

页数：2

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