Solid-phase organic chemistry:: Synthesis of 2β-(heterocyclylthiomethyl)penam derivatives on solid support

被引：4
|
作者：
Delpiccolo, CML [1 ]
Mata, EG [1 ]
机构：
[1] Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, CONICET, Inst Quim Organ Sintesis, RA-2000 Rosario, Santa Fe, Argentina
来源：
MOLECULES | 2000年 / 5卷 / 03期
关键词：
D O I：
10.3390/50300537
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The synthesis of 2 beta-(heterocyclylthiomethyl)penam derivatives on solid support has been developed. Compounds are obtained in good to high yields (based on loading of the original resin). The key step is the solid-phase double rearrangement of the corresponding penicillin sulfoxide.
引用
收藏
页码：537 / 538
页数：2
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