Cul-catalyzed cross-coupling of terminal alkynes with dialkoxycarbenes: a general method for the synthesis of unsymmetrical propargylic acetals

被引：9
|
作者：
Xiao, Tiebo [1 ]
Zhang, Ping [1 ]
Xie, Yang [1 ]
Wang, Jun [1 ]
Zhou, Lei [1 ]
机构：
[1] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 32期
基金：
中国国家自然科学基金;
关键词：
TETHERED TRIPLE BONDS; N-TOSYLHYDRAZONES; METAL CARBENE; H INSERTION; CASCADE; DIMETHOXYCARBENE; STRAIGHTFORWARD; REAGENTS; ROUTE;
D O I：
10.1039/c4ob00614c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A general source of dialkoxycarbenes, 2,2-dialkoxy-5,5-dimethyl-Delta(3)-1,3,4-oxadiazotines, have been successfully employed as coupling partners in Cul-catalyzed cross-coupling reactions with terminal alkynes, which afforded various unsymmetrical propargylic acetats in good yields.
引用
收藏
页码：6215 / 6222
页数：8
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