Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases

被引：47
|
作者：
Rao, N. Vijayakameswara [1 ,2 ]
Rho, Jun Gi [3 ]
Um, Wooram [1 ]
EK, Pramod Kumar [1 ]
Nguyen, Van Quy [1 ]
Oh, Byeong Hoon [1 ]
Kim, Wook [3 ]
Park, Jae Hyung [1 ,4 ]
机构：
[1] Sungkyunkwan Univ, Sch Chem Engn, Suwon 16419, South Korea
[2] Natl Taiwan Univ Sci & Technol, Dept Chem Engn, Taipei 10617, Taiwan
[3] Ajou Univ, Dept Mol Sci & Technol, Suwon 16499, South Korea
[4] Sungkyunkwan Univ, Dept Biomed Inst Convergence SKKU BICS, Suwon 16419, South Korea
来源：
PHARMACEUTICS | 2020年 / 12卷 / 10期
基金：
新加坡国家研究基金会;
关键词：
hyaluronic acid; drug conjugates; polymeric nanoparticles; tumor-targeting; targeted-therapy; inflammatory diseases; type; 2; diabetes; atherosclerosis; GENOME-WIDE ASSOCIATION; MOLECULAR-WEIGHT; INSULIN-RESISTANCE; ORAL DELIVERY; RECEPTOR CD44; TISSUE-INJURY; IN-VIVO; TUMOR; MACROPHAGES; NANOCARRIERS;
D O I：
10.3390/pharmaceutics12100931
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-specific and long-acting nanocarriers for the delivery of a wide range of therapeutic or diagnostic agents. Recently, it has been demonstrated that empty HA-NPs without bearing any therapeutic agent can be used therapeutically for the treatment of inflammatory diseases via modulating inflammatory responses. In this review, we aim to provide an overview of the significant achievements in this field and highlight the potential of HA-NPs for the treatment of inflammatory diseases.
引用
收藏
页码：1 / 18
页数：18
相关论文
共 50 条
  • [21] Anti-inflammatory and Antioxidant Potential of Hyaluronic Acid Mediated Zinc Nanoparticles
    Akash, N.
    Arivarasu, Lakshminarayanan
    Rajeshkumar, S.
    JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2020, 32 (20) : 33 - 37
  • [22] Combination of urea-crosslinked hyaluronic acid and sodium ascorbyl phosphate for the treatment of inflammatory lung diseases: An in vitro study
    Fallacara, Arianna
    Busato, Laura
    Pozzoli, Michele
    Ghadiri, Maliheh
    Ong, Hui Xin
    Young, Paul M.
    Manfredini, Stefano
    Traini, Daniela
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 120 : 96 - 106
  • [23] Development of a novel hyaluronic acid membrane for the treatment of ocular surface diseases
    Kim, Dong Ju
    Jung, Mi-Young
    Pak, Ha-Jin
    Park, Joo-Hee
    Kim, Martha
    Chuck, Roy S.
    Park, Choul Yong
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [24] Development of a novel hyaluronic acid membrane for the treatment of ocular surface diseases
    Dong Ju Kim
    Mi-Young Jung
    Ha-Jin Pak
    Joo-Hee Park
    Martha Kim
    Roy S. Chuck
    Choul Yong Park
    Scientific Reports, 11
  • [25] Hyaluronic acid-shelled, peptide drug conjugate-cored nanomedicine for the treatment of hepatocellular carcinoma
    Wang, Jingjing
    Qian, Ying
    Xu, Liu
    Shao, Yurou
    Zhang, Hu
    Shi, Fanli
    Chen, Jiaxin
    Cui, Siqi
    Chen, Xiaoyan
    Zhu, Dongwei
    Hu, Rongfeng
    Chen, Zhipeng
    Materials Science and Engineering C, 2020, 117
  • [26] Hyaluronic acid-shelled, peptide drug conjugate-cored nanomedicine for the treatment of hepatocellular carcinoma
    Wang, Jingjing
    Qian, Ying
    Xu, Liu
    Shao, Yurou
    Zhang, Hu
    Shi, Fanli
    Chen, Jiaxin
    Cui, Siqi
    Chen, Xiaoyan
    Zhu, Dongwei
    Hu, Rongfeng
    Chen, Zhipeng
    MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2020, 117
  • [27] The role of hyaluronic acid in the design and functionalization of nanoparticles for the treatment of colorectal cancer
    de Paula, Mariana Carlomagno
    Carvalho, Suzana Goncalves
    Silvestre, Amanda Leticia Polli
    dos Santos, Aline Martins
    Meneguin, Andreia Bagliotti
    Chorilli, Marlus
    CARBOHYDRATE POLYMERS, 2023, 320
  • [28] Chitosan-hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma
    Oyarzun-Ampuero, F. A.
    Brea, J.
    Loza, M. I.
    Torres, D.
    Alonso, M. J.
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2009, 381 (02) : 122 - 129
  • [29] Targeted hyaluronic acid nanoparticles improve treatment response in pancreatic cancer
    Jajja, Mohammad Raheel
    Zhu, Lei
    Wang, Dazhi
    Staley, Charles A.
    El-Rayes, Bassel
    Kooby, David A.
    Yang, Lily
    CANCER RESEARCH, 2019, 79 (13)
  • [30] Nitric oxide-scavenging hyaluronic acid nanoparticles for osteoarthritis treatment
    Nah, Yunyoung
    Sobha, Sivasangu
    Saravanakumar, Gurusamy
    Kang, Byung-Yoon
    Yoon, Joo-Byoung
    Kim, Won Jong
    BIOMATERIALS SCIENCE, 2024, 12 (06) : 1477 - 1489
12345