Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases

被引：47
|
作者：
Rao, N. Vijayakameswara [1 ,2 ]
Rho, Jun Gi [3 ]
Um, Wooram [1 ]
EK, Pramod Kumar [1 ]
Nguyen, Van Quy [1 ]
Oh, Byeong Hoon [1 ]
Kim, Wook [3 ]
Park, Jae Hyung [1 ,4 ]
机构：
[1] Sungkyunkwan Univ, Sch Chem Engn, Suwon 16419, South Korea
[2] Natl Taiwan Univ Sci & Technol, Dept Chem Engn, Taipei 10617, Taiwan
[3] Ajou Univ, Dept Mol Sci & Technol, Suwon 16499, South Korea
[4] Sungkyunkwan Univ, Dept Biomed Inst Convergence SKKU BICS, Suwon 16419, South Korea
来源：
PHARMACEUTICS | 2020年 / 12卷 / 10期
基金：
新加坡国家研究基金会;
关键词：
hyaluronic acid; drug conjugates; polymeric nanoparticles; tumor-targeting; targeted-therapy; inflammatory diseases; type; 2; diabetes; atherosclerosis; GENOME-WIDE ASSOCIATION; MOLECULAR-WEIGHT; INSULIN-RESISTANCE; ORAL DELIVERY; RECEPTOR CD44; TISSUE-INJURY; IN-VIVO; TUMOR; MACROPHAGES; NANOCARRIERS;
D O I：
10.3390/pharmaceutics12100931
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-specific and long-acting nanocarriers for the delivery of a wide range of therapeutic or diagnostic agents. Recently, it has been demonstrated that empty HA-NPs without bearing any therapeutic agent can be used therapeutically for the treatment of inflammatory diseases via modulating inflammatory responses. In this review, we aim to provide an overview of the significant achievements in this field and highlight the potential of HA-NPs for the treatment of inflammatory diseases.
引用
收藏
页码：1 / 18
页数：18
相关论文
共 50 条
  • [1] Self-assembled hyaluronic acid nanoparticles: Implications as a nanomedicine for treatment of type 2 diabetes
    Rho, Jun Gi
    Han, Hwa Seung
    Han, Ji Hye
    Lee, Hansang
    Van Quy Nguyen
    Lee, Wang Hee
    Kwon, Seunglee
    Heo, Sungeun
    Yoon, Juhwan
    Shin, Han Ho
    Lee, Eun-young
    Kang, Hoin
    Yang, Siyoung
    Lee, Eun Kyung
    Park, Jae Hyung
    Kim, Wook
    JOURNAL OF CONTROLLED RELEASE, 2018, 279 : 89 - 98
  • [2] Self-assembled hyaluronic acid nanoparticles for the topical treatment of inflammatory skin diseases: Beyond drug carriers
    Lee, Wang Hee
    Kim, Wook
    JOURNAL OF CONTROLLED RELEASE, 2024, 366 : 114 - 127
  • [3] PEGylated crosslinked hyaluronic acid nanoparticles designed through a microfluidic platform for nanomedicine
    Russo, Maria
    Grimaldi, Anna Maria
    Bevilacqua, Paolo
    Tammaro, Olimpia
    Netti, Paolo Antonio
    Torino, Enza
    NANOMEDICINE, 2017, 12 (18) : 2211 - 2222
  • [4] Piperine-loaded nanoparticles incorporated into hyaluronic acid/sodium alginate-based membranes for the treatment of inflammatory skin diseases
    Politi, Flavio Augusto Sanches
    Carvalho, Suzana Goncalves
    Rodero, Camila Fernanda
    dos Santos, Kaio Pini
    Meneguin, Andreia Bagliotti
    Sorrechia, Rodrigo
    Chiavacci, Leila Aparecida
    Chorilli, Marlus
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 227 : 736 - 748
  • [5] Nanomedicine: evolutionary and revolutionary developments in the treatment of certain inflammatory diseases
    Istvan Szelenyi
    Inflammation Research, 2012, 61 : 1 - 9
  • [6] Nanomedicine: evolutionary and revolutionary developments in the treatment of certain inflammatory diseases
    Szelenyi, Istvan
    INFLAMMATION RESEARCH, 2012, 61 (01) : 1 - 9
  • [7] Efficacy of hyaluronic acid in the treatment of nasal inflammatory diseases: a systematic review and meta-analysis
    Liu, Huixia
    Chen, Yue
    Wang, Huan
    Luo, Xinyi
    Xie, Dengpiao
    Ji, Qing
    Tian, Li
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [8] Hyaluronic acid-conjugated liposomes loaded with dexamethasone: A promising approach for the treatment of inflammatory diseases
    Japiassu, Kamila Bohne
    Fay, Francois
    Marengo, Alessandro
    Mendanha, Sebastiao A.
    Cailleau, Catherine
    Louaguenouni, Younes
    Wang, Qinglin
    Denis, Stephanie
    Tsapis, Nicolas
    Nascimento, Thais Leite
    Lima, Eliana Martins
    Fattal, Elias
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 639
  • [9] Recent developments in hyaluronic acid-based nanomedicine for targeted cancer treatment
    Rao, N. Vijayakameswara
    Yoon, Hong Yeol
    Han, Hwa Seung
    Ko, Hyewon
    Son, Soyoung
    Lee, Minchang
    Lee, Hansang
    Jo, Dong-Gyu
    Kang, Young Mo
    Park, Jae Hyung
    EXPERT OPINION ON DRUG DELIVERY, 2016, 13 (02) : 239 - 252
  • [10] Potential Use of Nanomedicine for the Anti-inflammatory Treatment of Neurodegenerative Diseases
    Dolores Cayero-Otero, Maria
    Espinosa-Oliva, Ana M.
    Herrera, Antonio J.
    Garcia-Dominguez, Irene
    Fernandez-Arevalo, Mercedes
    Martin-Banderas, Lucia
    de Pablos, Rocio M.
    CURRENT PHARMACEUTICAL DESIGN, 2018, 24 (14) : 1589 - 1616
12345