Isothermal Amplification Strategies for Detection in Microfluidic Devices

被引：18
|
作者：
Sarkar, Saheli [1 ]
Sabhachandani, Pooja [1 ]
Konry, Tania [1 ]
机构：
[1] Northeastern Univ, Dept Pharmaceut Sci, 360 Huntington Ave, Boston, MA 02115 USA
来源：
TRENDS IN BIOTECHNOLOGY | 2017年 / 35卷 / 03期
关键词：
SINGLE CELLS; CIRCLE AMPLIFICATION; LIGATION ASSAYS; CHIP; PROTEOME;
D O I：
10.1016/j.tibtech.2016.09.006
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Isothermal rolling circle amplification (RCA) is used to detect nucleic and non-nucleic acid biomarkers with high sensitivity. Immuno-RCA, the specific detection of proteins via antigen-antibody recognition, has been miniaturized for micro fluidic platforms to reduce reagent and sample consumption, accelerate reaction kinetics, and enhance the sensitivity and specificity of detection.
引用
收藏
页码：186 / 189
页数：4
相关论文
共 50 条
  • [41] Rapid Detection of Streptococcus mutans Using an Integrated Microfluidic System with Loop-Mediated Isothermal Amplification
    Wang, Jingfu
    Wang, Jingyi
    Chang, Xin
    Shang, Jin
    Wang, Yuehui
    Ma, Qin
    Shen, Liangliang
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2023, 33 (08) : 1101 - 1110
  • [42] Detection of viral DNA by isothermal NASBA amplification and chemiluminescence gene probe hybridization assay in a microfluidic cartridge
    Bonvicini, F.
    Mirasoli, M.
    Zangheri, M.
    Nascetti, A.
    De Cesare, G.
    Caputo, D.
    Roda, A.
    Gallinella, G.
    JOURNAL OF CLINICAL VIROLOGY, 2015, 70 : S91 - S92
  • [43] A highly sensitive, real-time centrifugal microfluidic chip for multiplexed detection based on isothermal amplification
    Dong, Xiaobin
    Tang, Zhiqian
    Jiang, Xiaodan
    Fu, Qiang
    Xu, Donglin
    Zhang, Lulu
    Qiu, Xianbo
    TALANTA, 2024, 268
  • [44] A loop-mediated isothermal amplification-based microfluidic chip for triplex detection of shrimp pathogens
    Hu, Keshun
    Li, Ye
    Wang, Feng
    Liu, Jianying
    Li, Yuanyuan
    Zhao, Qian
    Zheng, Xiaoye
    Zhu, Ningyu
    Yu, Xiaoping
    Fang, Shaohua
    Huang, Jun
    JOURNAL OF FISH DISEASES, 2023, 46 (02) : 137 - 146
  • [45] Quadratic isothermal amplification for the detection of microRNA
    Ruixue Duan
    Xiaolei Zuo
    Shutao Wang
    Xiyun Quan
    Dongliang Chen
    Zhifei Chen
    Lei Jiang
    Chunhai Fan
    Fan Xia
    Nature Protocols, 2014, 9 : 597 - 607
  • [46] Detection of Tetracycline using Isothermal Amplification
    Wu, Chia-Cheng
    Wu, Li-An
    Chen, Yih-Fan
    Chou, Lu-Ting
    2017 IEEE 12TH INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS (NEMS), 2017, : 210 - 213
  • [47] Quadratic isothermal amplification for the detection of microRNA
    Duan, Ruixue
    Zuo, Xiaolei
    Wang, Shutao
    Quan, Xiyun
    Chen, Dongliang
    Chen, Zhifei
    Jiang, Lei
    Fan, Chunhai
    Xia, Fan
    NATURE PROTOCOLS, 2014, 9 (03) : 597 - 607
  • [48] Microfluidic devices for detection ofRNAviruses
    Basiri, Arefeh
    Heidari, Arash
    Nadi, Melina Farshbaf
    Fallahy, Mohammad Taha Pahlevan
    Nezamabadi, Sasan Salehi
    Sedighi, Mohammadreza
    Saghazadeh, Amene
    Rezaei, Nima
    REVIEWS IN MEDICAL VIROLOGY, 2021, 31 (01) : 1 - 11
  • [49] Naked-eye detection strategies coupled with isothermal nucleic acid amplification techniques for the detection of human pathogens
    Garrido-Maestu, Alejandro
    Prado, Marta
    COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2022, 21 (02): : 1913 - 1939
  • [50] Rapid detection of multiple pathogens by the combined loop-mediated isothermal amplification technology and microfluidic chip technology
    Ou, Hongling
    Wang, Yan
    Wang, Qiyuan
    Ma, Yingying
    Liu, Chen
    Jia, Lianling
    Zhang, Qiaoyun
    Li, Mengwen
    Feng, Xinxin
    Li, Meng
    Wang, Xinru
    Wang, Chengbin
    ANNALS OF PALLIATIVE MEDICINE, 2021, 10 (10) : 11053 - 11066
12345