Isothermal Amplification Strategies for Detection in Microfluidic Devices

被引：18
|
作者：
Sarkar, Saheli [1 ]
Sabhachandani, Pooja [1 ]
Konry, Tania [1 ]
机构：
[1] Northeastern Univ, Dept Pharmaceut Sci, 360 Huntington Ave, Boston, MA 02115 USA
来源：
TRENDS IN BIOTECHNOLOGY | 2017年 / 35卷 / 03期
关键词：
SINGLE CELLS; CIRCLE AMPLIFICATION; LIGATION ASSAYS; CHIP; PROTEOME;
D O I：
10.1016/j.tibtech.2016.09.006
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Isothermal rolling circle amplification (RCA) is used to detect nucleic and non-nucleic acid biomarkers with high sensitivity. Immuno-RCA, the specific detection of proteins via antigen-antibody recognition, has been miniaturized for micro fluidic platforms to reduce reagent and sample consumption, accelerate reaction kinetics, and enhance the sensitivity and specificity of detection.
引用
收藏
页码：186 / 189
页数：4
相关论文
共 50 条
  • [21] Mayaro virus detection by integrating sample preparation with isothermal amplification in portable devices
    Alipanah, Morteza
    Manzanas, Carlos
    Hai, Xin
    Lednicky, John A.
    Paniz-Mondolfi, Alberto
    Morris, J. Glenn
    Fan, Z. Hugh
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2023, 415 (23) : 5605 - 5617
  • [22] Mayaro virus detection by integrating sample preparation with isothermal amplification in portable devices
    Morteza Alipanah
    Carlos Manzanas
    Xin Hai
    John A. Lednicky
    Alberto Paniz-Mondolfi
    J. Glenn Morris
    Z. Hugh Fan
    Analytical and Bioanalytical Chemistry, 2023, 415 : 5605 - 5617
  • [23] Microfluidic devices harboring unsealed reactors for real-time isothermal helicase-dependent amplification
    Ramalingam, Naveen
    San, Tong Chee
    Kai, Teo Jin
    Mak, Matthew Yew Mun
    Gong, Hai-Qing
    MICROFLUIDICS AND NANOFLUIDICS, 2009, 7 (03) : 325 - 336
  • [24] Microfluidic devices harboring unsealed reactors for real-time isothermal helicase-dependent amplification
    Naveen Ramalingam
    Tong Chee San
    Teo Jin Kai
    Matthew Yew Mun Mak
    Hai-Qing Gong
    Microfluidics and Nanofluidics, 2009, 7 : 325 - 336
  • [25] Multivalent aptasensor array and silver aggregated amplification for multiplex detection in microfluidic devices
    Liu, Xiaohui
    Li, Hui
    Zhao, Yaju
    Yu, Xiaodong
    Xu, Danke
    TALANTA, 2018, 188 : 417 - 422
  • [26] Signal amplification strategies for microfluidic immunoassays
    Giri, Basant
    Pandey, Binod
    Neupane, Bhanu
    Ligler, Frances S.
    TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2016, 79 : 326 - 334
  • [27] Isothermal Polymerase Amplification in a Centrifugal Microfluidic Foil Cartridge
    Lutz, S.
    Weber, P.
    Focke, M.
    Faltin, B.
    Roth, G.
    Piepenburg, O.
    Armes, N.
    Mark, D.
    Zengerle, R.
    von Stetten, F.
    PROCEEDINGS OF THE EUROSENSORS XXIII CONFERENCE, 2009, 1 (01): : 529 - +
  • [28] A microfluidic lab-on-a-disc integrated loop mediated isothermal amplification for foodborne pathogen detection
    Sayad, Abkar Ahmed
    Ibrahim, Fatimah
    Uddin, Shah Mukim
    Pei, Koh Xiu
    Mohktar, Mas S.
    Madou, Marc
    Kwai Lin Thong
    SENSORS AND ACTUATORS B-CHEMICAL, 2016, 227 : 600 - 609
  • [29] Optimization of the Amplicons Detection System of Loop-Mediated Isothermal Amplification on Microfluidic Compact Disk
    Uddin, Shah Mukim
    Ibrahim, Fatimah
    Cho, Jongman
    Thong, Kwai Lin
    INTERNATIONAL CONFERENCE ON BIOMEDICAL AND HEALTH INFORMATICS, 2019, 64 : 7 - 12
  • [30] Author Correction: Bioluminescent detection of isothermal DNA amplification in microfluidic generated droplets and artificial cells
    Patrick Hardinge
    Divesh K. Baxani
    Thomas McCloy
    James A. H. Murray
    Oliver K. Castell
    Scientific Reports, 11
12345