Passerini Multicomponent Reaction of Indane-1,2,3-Trione: an Efficient Route for the One-Pot Synthesis of Sterically Congested 2,2-Disubstituted Indane-1,3-Dione Derivatives

被引：65

作者：

Kazemizadeh, Ali Reza ^{[1
]}

Ramazani, Ali ^{[1
]}

机构：

[1] Zanjan Univ, Dept Chem, Zanjan, Iran

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2009年 / 20卷 / 02期

关键词：

indane-1,2,3-trione; isocyanide; Passerini reaction; benzoic acid; DIALKYL ACETYLENEDICARBOXYLATES; STEREOSELECTIVE-SYNTHESIS; ALPHA-AMINOALDEHYDES; 3-COMPONENT REACTION; ISOCYANIDES; CHEMISTRY; (N-ISOCYANIMINO)TRIPHENYLPHOSPHORANE; INHIBITORS; ACID;

D O I：

10.1590/S0103-50532009000200016

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Passerini reaction of indane-1,2,3-trione, isocyanides and benzoic acid derivatives proceed at room temperature and sterically congested 2,2-disubstituted indane-1,3-dione derivatives are synthesized in excellent yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions are observed.

引用

页码：309 / 312

页数：4

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