Synthesis of novel 4-(5′-pyrrolidinyl)-β-lactams

被引：45

作者：

Grigg, R ^{[1
]}

Thornton-Pett, M ^{[1
]}

Xu, J ^{[1
]}

Xu, LH ^{[1
]}

机构：

[1] Univ Leeds, Sch Chem, Mol Innovat Divers & Automated Synth Ctr, Leeds LS2 9JT, W Yorkshire, England

来源：

TETRAHEDRON | 1999年 / 55卷 / 48期

关键词：

beta-lactams; azomethine ylide; cycloaddition; cascade reaction;

D O I：

10.1016/S0040-4020(99)00867-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of novel 4-(5'-pynolidinyl)-beta-lactams from imines derived from 4-formyl-beta-lactams and alpha-amino esters via cascade imine-->azomethine ylide-->1,3-dipolar cycloaddition reactions is described. These cascades are endo-specific, exhibit facial stereoselectivity and occur in good to excellent yields. (C) 1999 Elsevier Science Ltd. Ail rights reserved.

引用

页码：13841 / 13866

页数：26

共 50 条

[21] A facile route for the synthesis of novel γ-lactams
Kumar, KRR
Mallesha, H
Basappa
Rangappa, KS
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2003, 40 (04) : 607 - 609
[22] Novel synthesis of β-lactams and their biological evaluation
Banik, Bimal K.
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2014, 91 (10) : 1837 - 1860
[23] Novel Method for the Enantioselective Synthesis of β-Lactams
YUAN Qing
ChemicalResearchinChineseUniversities, 2008, (01) : 58 - 64
[24] SYNTHESIS OF NOVEL BETA-LACTAMS
REN, XF
TUROS, E
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 253 - ORGN
[25] A NOVEL SYNTHESIS OF BETA-LACTAMS
ALPER, H
PERERA, CP
AHMED, FR
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (05) : 1289 - 1291
[26] Synthesis of novel monocyclic β-lactams.
Amry, A
Konaklieva, MI
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 220 : U167 - U167
[27] Synthesis of novel spiro-β-lactams
Arora, Renu
Venugopalan, P.
Bari, S. S.
JOURNAL OF CHEMICAL SCIENCES, 2010, 122 (02) : 125 - 135
[28] Synthesis of novel optically pure β-lactams
Yang, Y
Wang, FY
Rochon, FD
Kayser, MM
CANADIAN JOURNAL OF CHEMISTRY, 2005, 83 (01) : 28 - 36
[29] Novel method for the enantioselective synthesis of β-lactams
Yuan Qing
Han Shan-zhong
Wang Yan-guang
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2008, 24 (01) : 58 - 64
[30] Synthesis of novel spiro-β-lactams
Renu Arora
P. Venugopalan
S. S. Bari
Journal of Chemical Sciences, 2010, 122 : 125 - 135

← 1 2 3 4 5 →