Two new sesquiterpene lactones from the fruits of Illicium jiadifengpi

被引：7
|
作者：
Liu, Jifeng [1 ]
Liu, Feiyan [1 ]
Zhang, Nenling [2 ]
Wang, Yafeng [1 ,3 ]
Yang, Lijia [1 ]
Bi, Yuefeng [1 ]
Zhang, Yanbing [1 ]
Liu, Mengqi [4 ]
机构：
[1] Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Peoples R China
[2] Guiyang Med Univ, Sch Pharm, Guiyang 550004, Peoples R China
[3] Zhengzhou Univ, Acad Med & Pharmaceut Sci, Henan Key Lab Pharmacol Liver Dis, Zhengzhou 450052, Peoples R China
[4] Henan Univ Tradit Chinese Med, Sch Pharmaceut Sci, Zhengzhou 450008, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Illicium jiadifengpi; sesquiterpene lactones; anti-HBV activity; NEUROTROPHIC ACTIVITY; ROOTS;
D O I：
10.1080/14786419.2015.1058793
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new seco-prezizaane-type sesquiterpenes, 3,4-dehydroneomajucin (1) and 1,2,3,4-tetradehydroneomajucin (2), were isolated from the fruits of Illicium jiadifengpi. The structure of these compounds was determined using 1D and 2D NMR and ESI-MS. The isolates were evaluated for their anti-hepatitis B virus activities on the Hep G2.2.15 cell line. The inhibitory rates of compounds 1 and 2 on the HBeAg and HBsAg expression were 30.08 +/- 3.09% and 11.43 +/- 1.92% at a concentrations of 68.00M and 7.88 +/- 1.21% and 16.96 +/- 4.24% at a concentration of 68.50M, respectively.
引用
收藏
页码：322 / 326
页数：5
相关论文
共 50 条
  • [31] Unusual nor-sesquiterpene lactone from the fruits of Illicium henryi
    Liu, Ji-Feng
    Wang, Ya-Feng
    Bi, Ya-Ping
    Li, Hui-Juan
    Jia, Lu
    Bi, Yue-Feng
    Zhang, Yan-Bing
    TETRAHEDRON LETTERS, 2013, 54 (36) : 4834 - 4836
  • [32] SESQUITERPENE LACTONES FROM THE FRUITS OF SMYRNIUM-ROTUNDIFOLIUM
    GOREN, N
    ULUBELEN, A
    JAKUPOVIC, J
    BOHLMANN, F
    GRENZ, M
    PHYTOCHEMISTRY, 1984, 23 (10) : 2281 - 2284
  • [33] SESQUITERPENE LACTONES FROM THE FRUITS OF SMYRNIUM-CONNATUM
    GOREN, N
    ULUBELEN, A
    PHYTOCHEMISTRY, 1987, 26 (09) : 2633 - 2634
  • [34] Two new halogenated sesquiterpene lactones from Palisada intermedia
    Doan, Vuong Trung
    Pham, Van Thong
    Le, Chi Hien Dat
    Luu, Thi Thanh Nhan
    Dam, To Uyen
    Le, Ho Khanh Hy
    Ton That, Quang
    Nguyen, Kim Phi Phung
    Ngo, Thi Thuy Duong
    NATURAL PRODUCT RESEARCH, 2024, 38 (13) : 2258 - 2263
  • [35] Two new sesquiterpene lactones from the leaves of Laurus nobilis
    Dall'Acqua, Stefano
    Viola, Giampietro
    Giorgetti, Michela
    Loi, Maria Cecilia
    Innocenti, Gabbriella
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2006, 54 (08) : 1187 - 1189
  • [36] Two new sesquiterpene lactones from leaves of yacon, Smallanthus sonchifolius
    Ran, Xiao-Ku
    Aung, Khin Khin Win
    Bai, Jun
    Dou, Pei-Yuan
    Zeng, Zheng
    Dou, De-Qiang
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 20 (06) : 538 - 544
  • [37] Two New Eremophilane Sesquiterpene Lactones from Ligularia myriocephala Ling
    Jun Xi LIU1
    Chinese Chemical Letters, 2005, (12) : 1618 - 1620
  • [38] Two New Sesquiterpene Lactones and a Triterpene Glycoside from Cichorium glandulosum
    Wu, Hankui
    Su, Zhen
    Xin, Xuelei
    Aisa, Haji Akber
    HELVETICA CHIMICA ACTA, 2010, 93 (03) : 414 - 421
  • [39] Two new eremophilane sesquiterpene lactones from Ligularia myriocephala Ling
    Liu, JX
    Wei, XN
    Shi, YP
    Lu, RH
    CHINESE CHEMICAL LETTERS, 2005, 16 (12) : 1618 - 1620
  • [40] Two new sesquiterpene lactones from Montanoa tomentosa ssp microcephala
    Braca, A
    Cioffi, G
    Morelli, I
    Venturella, F
    Pizza, C
    De Tommasi, N
    PLANTA MEDICA, 2001, 67 (08) : 774 - 776
12345