Sarcophytolides G-L, New Biscembranoids from the Soft Coral Sarcophyton elegans

被引:13
|
作者
Xi, Zhifang [1 ]
Bie, Wei [1 ]
Chen, Wei [1 ]
Liu, Dong [1 ]
van Ofwegen, Leen [2 ]
Proksch, Peter [3 ]
Lin, Wenhan [1 ]
机构
[1] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
[2] Natl Museum Nat Hist Naturalis, NL-2300 Leiden, Netherlands
[3] Univ Dusseldorf, Inst Pharmaceut Biol & Biotechnol, DE-40225 Dusseldorf, Germany
关键词
Soft corals; Sarcophyton elegans; Isobiscembranoids; Biscembranoids; Sarcophytolides G-L; DIELS-ALDER PRECURSOR; LOBOPHYTUM-PAUCIFLORUM; MONOMERIC COUNTERPART; TORTUOSUM;
D O I
10.1002/hlca.201300086
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Six new biscembranoids, namely, sarcophytolides G-L (1-6, resp.), together with six known analogs, were isolated from a marine soft coral Sarcophyton elegans. The structures of the new compounds were established on the basis of 1D- and 2D-NMR (COSY, HSQC, HMBC, and NOESY) spectroscopic analysis together with the aid of MS, CD, and IR data. The unusual isobiscembranoid sarcophytolide G (1) was found for the first time in the genus Sarcophyton.
引用
收藏
页码:2218 / 2227
页数:10
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