Neat reaction technology for the synthesis of 4-oxo-thiazolidines derived from 2-SH-benzothiazole and antimicrobial screening of some synthesized 4-thiazolidinones

被引：39
|
作者：
Desai, K. G. [1 ]
Raval, J. P.
Desai, K. R.
机构：
[1] Veer Narmad S Gujarat Univ, Fac Sci, Dept Chem, Synth Organ Chem Res Lab, Surat, Gujarat, India
[2] VNSG Univ, Dept Chem, Ind Chem Div, Surat, Gujarat, India
[3] VNSG Univ, Fac Sci, Dept Chem, Div Organ Chem, Surat, Gujarat, India
来源：
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2006年 / 3卷 / 03期
关键词：
4-thiazolidinones; heterocyclization; microwave effect; antimicrobial activity;
D O I：
10.1007/BF03247213
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of 4-thiazolidinones 4a-j in a good yields from the heterocyclization reaction of 2-(benzothiazol-2-ylthio)-N'- benzylideneacetohydrazide 3a-j with SHCH2COOH in DMF in the presence of a catalytic amount of anhydrous ZnCl2 under microwave irradiation is described and compared with conventional synthesis methods. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral data. Some of the new compounds were tested against bacteria ( Gram - ve and Gram+ ve) and fungi.
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页码：233 / 241
页数：9
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