Neat reaction technology for the synthesis of 4-oxo-thiazolidines derived from 2-SH-benzothiazole and antimicrobial screening of some synthesized 4-thiazolidinones

被引：39
|
作者：
Desai, K. G. [1 ]
Raval, J. P.
Desai, K. R.
机构：
[1] Veer Narmad S Gujarat Univ, Fac Sci, Dept Chem, Synth Organ Chem Res Lab, Surat, Gujarat, India
[2] VNSG Univ, Dept Chem, Ind Chem Div, Surat, Gujarat, India
[3] VNSG Univ, Fac Sci, Dept Chem, Div Organ Chem, Surat, Gujarat, India
来源：
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2006年 / 3卷 / 03期
关键词：
4-thiazolidinones; heterocyclization; microwave effect; antimicrobial activity;
D O I：
10.1007/BF03247213
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of 4-thiazolidinones 4a-j in a good yields from the heterocyclization reaction of 2-(benzothiazol-2-ylthio)-N'- benzylideneacetohydrazide 3a-j with SHCH2COOH in DMF in the presence of a catalytic amount of anhydrous ZnCl2 under microwave irradiation is described and compared with conventional synthesis methods. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral data. Some of the new compounds were tested against bacteria ( Gram - ve and Gram+ ve) and fungi.
引用
收藏
页码：233 / 241
页数：9
相关论文
共 44 条
  • [21] SYNTHESIS OF SOME QUINAZOLINES DERIVED FROM 6,8-DIBROMO2-(2-CARBOXY-PHENYL)-4H-3,1-BENZOXAZIN-4-ONE AS ANTIMICROBIAL AGENTS
    Nassar, I. F.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2009, 45 (12) : 1515 - 1522
  • [22] Synthesis of some schiff bases,thiazolidinones and azetidinones derived from 2,6-diaminobenzo[1,2-d:4,5-d′] bisthiazole and their anticancer activities
    Desai, SB
    Desai, PB
    Desai, KR
    HETEROCYCLIC COMMUNICATIONS, 2001, 7 (01) : 83 - 90
  • [23] Synthesis of some novel isoxazolyl pyrimido[4,5-d][1,3]-thiazol-7-ones, isoxazolyl-2-(4-oxo-4H-1,3-benzothiazin-2-yl)acetamides and isoxazolyl thiazolidinones from isoxazolyl cyanoacetamide synthon
    Rajanarendar, E.
    Murthy, K. Rama
    Reddy, M. Nagi
    Reddy, K. Govardhan
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2011, 50 (05): : 721 - 728
  • [24] Regioselective reaction: Synthesis of novel Mannich bases derived from 3-(4,6-disubstituted-2-thiomethylpyrimidyl)-4-amino-5-mercapto-1,2-4-triazoles and their antimicrobial properties
    Lingappa, B.
    Girisha, K. S.
    Kalluraya, Balakrishna
    Rai, N. Satheesh
    Kumari, Nalilu Suchetha
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2008, 47 (12): : 1858 - 1864
  • [25] Transformation of Schiff bases derived from α-naphthaldehyde.: Synthesis, spectral data and biological activity of new-3-aryl-2-(α-naphtyl)-4-thiazolidinones and N-aryl-N-[1-(α-naphthyl)but-3-enyl]amines
    Kouznetsov, V
    Rodríguez, W
    Stashenko, E
    Ochoa, C
    Vega, C
    Rolón, M
    Pereira, DM
    Escario, JA
    Barrio, AG
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 41 (06) : 995 - 999
  • [26] Heterocyclization of Isoniazid: Synthesis and Antimicrobial Activity of Some New Pyrimidine, 1, 3-Thiazole, 1, 2, 4-Thiadiazole, and 1, 2, 4-Triazole Derivatives Derived from Isoniazid
    Farhan, Mona E.
    Assy, Mohammed G.
    EGYPTIAN JOURNAL OF CHEMISTRY, 2019, 62 (02): : 171 - 180
  • [27] Spectroscopic characterization, thermogravimetric and antimicrobial studies of some new metal complexes derived from4-(4-Isopropyl phenyl)-2-oxo-6-phenyl 1,2-dihyropyridine-3-carbonitrile (L)
    Sadeek, S. A.
    Mohamed, A. A.
    El-Sayed, H. A.
    El-Attar, M. S.
    APPLIED ORGANOMETALLIC CHEMISTRY, 2020, 34 (02)
  • [28] Synthesis, characterization, antimicrobial activities, anticancer of some new pyridines from 2, 3-dihydro-2-oxo-4-phenyl-6-(thien-2-yl) pyridine-3-carbonitrile
    Elewa, Safaa, I
    Abdelhamid, Abdou O.
    Hamed, Ahmed A.
    Mansour, Eman
    SYNTHETIC COMMUNICATIONS, 2021, 51 (01) : 151 - 161
  • [29] Synthesis, characterization and antimicrobial activity of some new azo dyes derived from 4-hydroxy-6-methyl-2H-pyran-2-one and its dihydro derivative
    Ben Mohamed-Smati, Soumaya
    Faraj, Fadhil Lafta
    Becheker, Imene
    Berredjem, Hadjira
    Le Bideau, Franck
    Hamdi, Maamar
    Dumas, Francoise
    Rachedi, Yahia
    DYES AND PIGMENTS, 2021, 188
  • [30] Synthesis, characterization and screening of antimicrobial, antituberculosis, antiviral and anticancer activity of novel 1,3-thiazolidine-4-ones derived from 1-[2-(benzoylamino)-4-(methylthio)butyryl]-4-alkyl/arylalkyl thiosemicarbazides
    Tatar, Esra
    Kuecuekguezel, Ilkay
    De Clercq, Erik
    Sahin, Fikrettin
    Guelluece, Medine
    ARKIVOC, 2008, : 191 - 210
12345