Geometric calibration method based micro-CT system for small-animal imaging

被引：0

作者：

Hu, Zhanli ^{[1
,2
]}

Zou, Jing ^{[1
,2
]}

Gui, Jianbao ^{[1
,2
]}

Rong, Junyan ^{[1
,2
]}

Li, Yanming ^{[1
,2
]}

Zheng, Hairong ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Paul C Lauterbur Res Ctr Biomed Imaging, Shenzhen Inst Adv Technol, Inst Biomed & Hlth Engn, Shenzhen, Peoples R China

[2] Chinese Acad Sci, Key Lab Biomed Informat & Hlth Engn, Beijing 100864, Peoples R China

来源：

2010 4TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING (ICBBE 2010) | 2010年

关键词：

x-ray; micro-CT; geometric calibration; smallanimal imaging; CONE-BEAM TOMOGRAPHY; FLAT-PANEL DETECTOR; MICROTOMOGRAPHY; PARAMETERS; SCANNER;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Small-animal imaging technology has been rapidly developed for longitudinal screening of laboratory animals raised with disease developments or genetic manipulations. Micro-CT is a noninvasive imaging modality used to assess morphology and function in small-animal imaging. Geometric calibration involves the estimation of a set of parameters that describes the geometry of such systems, and is essential for accurate image reconstruction. Noo F et al (2000) have proposed a new analytic method for calibration of x-ray cone-beam scanners that use a circular path for the cone vertex. In this paper, we use this analytic calibration method for the estimation of the geometric parameters of a practical small-animal imaging micro-CT system. We improve calibration phantom of this method in order to make it more suitable for micro-CT system. The overall performance of the micro-CT system is demonstrated in some results of small-animal imaging. The projection images demonstrated that the adopt method is robust and easy to implement with high precision.

引用

页数：4

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