CCR 20th Anniversary Commentary: Autologous T Cells-The Ultimate Personalized Drug for the Immunotherapy of Human Cancer

被引:6
|
作者
Rosenberg, Steven A. [1 ]
机构
[1] NCI, Surg Branch, NIH, Bethesda, MD 20892 USA
关键词
TUMOR-INFILTRATING LYMPHOCYTES; METASTATIC MELANOMA; RECOMBINANT INTERLEUKIN-2; ADOPTIVE IMMUNOTHERAPY; ANTIGENS; REGRESSION; THERAPY;
D O I
10.1158/1078-0432.CCR-14-3131
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The article by Rosenberg and colleagues, which was published in the July 1, 2011, issue of Clinical Cancer Research, demonstrated the power of the adoptive transfer of autologous antitumor T cells to mediate the complete, durable, and likely curative regression of cancer in patients with heavily pretreated metastatic melanoma. It also provided a stimulus to the development of cell transfer approaches for other cancer types using both natural and genetically engineered lymphocytes. (C)2015 AACR.
引用
收藏
页码:5409 / 5411
页数:3
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