The article by Rosenberg and colleagues, which was published in the July 1, 2011, issue of Clinical Cancer Research, demonstrated the power of the adoptive transfer of autologous antitumor T cells to mediate the complete, durable, and likely curative regression of cancer in patients with heavily pretreated metastatic melanoma. It also provided a stimulus to the development of cell transfer approaches for other cancer types using both natural and genetically engineered lymphocytes. (C)2015 AACR.
机构:
Med Univ S Carolina, Dept Surg, Charleston, SC 29425 USA
Med Univ S Carolina, Hollings Canc Ctr, Charleston, SC 29425 USA
Ralph H Johnson VA Med Ctr, Charleston, SC USAMed Univ S Carolina, Dept Surg, Charleston, SC 29425 USA
Camp, E. Ramsay
Ellis, Lee M.
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Univ Texas MD Anderson Canc Ctr, Dept Surg Oncol, Houston, TX 77030 USA
Univ Texas MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USAMed Univ S Carolina, Dept Surg, Charleston, SC 29425 USA
机构:
Technion Israel Inst Technol, Ruth & Bruce Rappaport Fac Med, Haifa, IsraelTechnion Israel Inst Technol, Ruth & Bruce Rappaport Fac Med, Haifa, Israel
机构:
Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USA
Bashour, Sami I.
Ibrahim, Nuhad K.
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Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USA