Synthesis of some bicyclic oxazolo- and oxazepinopyrimidine derivatives

被引：3

作者：

Mobinikhaledi, A ^{[1
]}

Foroughifar, N ^{[1
]}

Ahmadi, B ^{[1
]}

机构：

[1] Univ Arak, Dept Chem, Arak, Iran

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2004年 / 179卷 / 09期

关键词：

1,2-dibromoethane; 1,4-dichlorobutane; 2-bromopropanoic acid; oxazepinopyrimidine; oxazolo;

D O I：

10.1080/10426500490466391

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Oxazolopyrimidine compounds 2(a-c) and 3(a-e) were synthesized by a simple one-pot condensation reaction of the pyrimidine derivatiue 1 with 1,2-dibroinoethane and 2-bromopropanoic acid, respectively. In a similar way the oxazepinopyrimidine compounds 4(a-b) were synthesized by reaction of 1 and 1,4-dichlorobutane in dioxcane under reflux condition. The yields of products following recrystallization were of the order of 55-85%.

引用

页码：1769 / 1775

页数：7

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