Synthesis of some bicyclic oxazolo- and oxazepinopyrimidine derivatives

被引：3
|
作者：
Mobinikhaledi, A [1 ]
Foroughifar, N [1 ]
Ahmadi, B [1 ]
机构：
[1] Univ Arak, Dept Chem, Arak, Iran
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2004年 / 179卷 / 09期
关键词：
1,2-dibromoethane; 1,4-dichlorobutane; 2-bromopropanoic acid; oxazepinopyrimidine; oxazolo;
D O I：
10.1080/10426500490466391
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Oxazolopyrimidine compounds 2(a-c) and 3(a-e) were synthesized by a simple one-pot condensation reaction of the pyrimidine derivatiue 1 with 1,2-dibroinoethane and 2-bromopropanoic acid, respectively. In a similar way the oxazepinopyrimidine compounds 4(a-b) were synthesized by reaction of 1 and 1,4-dichlorobutane in dioxcane under reflux condition. The yields of products following recrystallization were of the order of 55-85%.
引用
收藏
页码：1769 / 1775
页数：7
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