Radical-based regioselective cross-coupling of indoles and cycloalkanes

被引：24

作者：

Xiu, Jianmin ^{[1
]}

Yi, Wenbin ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Xiao Ling Wei St, Nanjing 210094, Jiangsu, Peoples R China

来源：

CATALYSIS SCIENCE & TECHNOLOGY | 2016年 / 6卷 / 04期

基金：

中国国家自然科学基金;

关键词：

2,3-DISUBSTITUTED INDOLES; SIMPLE ALKANES; ONE-POT; ALKYLATION; HETEROAROMATICS; ALKENYLATION; ARENES;

D O I：

10.1039/c5cy01907a

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An investigation into the regiochemistry of radical functionalization of indoles using cycloalkanes through di-tertbutyl peroxide (DTBP)-promoted C(sp(3))-H activation was conducted. A wide range of indoles bearing substituents at different positions was functionalized directly with simple cycloalkanes in moderate to high regioselectivity. 2-, 4- and 7-positions were mainly functionalized.

引用

页码：998 / 1002

页数：5

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