Radical-based regioselective cross-coupling of indoles and cycloalkanes

被引：24
|
作者：
Xiu, Jianmin [1 ]
Yi, Wenbin [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Xiao Ling Wei St, Nanjing 210094, Jiangsu, Peoples R China
来源：
CATALYSIS SCIENCE & TECHNOLOGY | 2016年 / 6卷 / 04期
基金：
中国国家自然科学基金;
关键词：
2,3-DISUBSTITUTED INDOLES; SIMPLE ALKANES; ONE-POT; ALKYLATION; HETEROAROMATICS; ALKENYLATION; ARENES;
D O I：
10.1039/c5cy01907a
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
An investigation into the regiochemistry of radical functionalization of indoles using cycloalkanes through di-tertbutyl peroxide (DTBP)-promoted C(sp(3))-H activation was conducted. A wide range of indoles bearing substituents at different positions was functionalized directly with simple cycloalkanes in moderate to high regioselectivity. 2-, 4- and 7-positions were mainly functionalized.
引用
收藏
页码：998 / 1002
页数：5
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