Universal reusable polymer support for oligonucleotide synthesis

被引:6
|
作者
Kumar, P [1 ]
Mahajan, S [1 ]
Gupta, KC [1 ]
机构
[1] Univ Delhi, Nucl Acids Res Lab, Inst Genom & Integrat Biol, Delhi 110007, India
来源
JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 19期
关键词
D O I
10.1021/jo049575v
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new efficient reusable universal polymer support for oligonucleotide synthesis, based on a non-ammoniacal cleavable linker, is described. Twenty six cycles of oligonucleotide synthesis have been carried out without compromising the quality of the fully deprotected oligonucleotides.
引用
收藏
页码:6482 / 6485
页数:4
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