Universal reusable polymer support for oligonucleotide synthesis

被引：6

作者：

Kumar, P ^{[1
]}

Mahajan, S ^{[1
]}

Gupta, KC ^{[1
]}

机构：

[1] Univ Delhi, Nucl Acids Res Lab, Inst Genom & Integrat Biol, Delhi 110007, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 19期

关键词：

D O I：

10.1021/jo049575v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new efficient reusable universal polymer support for oligonucleotide synthesis, based on a non-ammoniacal cleavable linker, is described. Twenty six cycles of oligonucleotide synthesis have been carried out without compromising the quality of the fully deprotected oligonucleotides.

引用

页码：6482 / 6485

页数：4

共 50 条

[21] POLYMER SUPPORT OLIGONUCLEOTIDE SYNTHESIS .20. SYNTHESIS OF A HENHECTACOSA DEOXYNUCLEOTIDE BY USE OF A DIMERIC PHOSPHORAMIDITE SYNTHON
WOLTER, A
BIERNAT, J
KOSTER, H
NUCLEOSIDES & NUCLEOTIDES, 1986, 5 (01): : 65 - 77
[22] OLIGONUCLEOTIDE SYNTHESIS WITH A SOLUBLE POLYMER AS CARRIER
CRAMER, F
HELBIG, R
HETTLER, H
SCHEIT, KH
SELIGER, H
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1966, 5 (06) : 601 - &
[23] OLIGONUCLEOTIDE SYNTHESIS ON A CROSSLINKED POLYACRYLMORPHOLIDE SUPPORT
NARANG, CK
BRUNFELDT, K
NORRIS, KE
TETRAHEDRON LETTERS, 1977, (21) : 1819 - 1822
[24] A NEW SUPPORT FOR AUTOMATED OLIGONUCLEOTIDE SYNTHESIS
MCCOLLUM, C
ANDRUS, A
NUCLEOSIDES & NUCLEOTIDES, 1991, 10 (1-3): : 573 - 574
[25] Oligonucleotide synthesis on linear reactive polymer grafted onto solid support, medical diagnostics applications
Minard-Basquin, C
Chaix, C
Pichot, C
Mandrand, B
NUCLEOSIDES & NUCLEOTIDES, 1999, 18 (6-7): : 1285 - 1287
[26] Novel advanced universal solid supports for oligonucleotide synthesis
Guzaev, AP
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U259 - U259
[27] Universal and reusable solide support thanks to a H-phosphonate diester linkage for the synthesis of single or multiple oligonucleotides
Ferreira, F
Meyer, A
Vasseur, JJ
Morvan, F
Chemistry of Nucleic Acid Components, 2005, 7 : 149 - 152
[28] A CONVENIENT SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDE 3'-PHOSPHATES
EFIMOV, VA
KALINKINA, AL
CHAKHMAKHCHEVA, OG
BIOORGANICHESKAYA KHIMIYA, 1995, 21 (08): : 612 - 616
[29] POLYMER SUPPORT SYNTHESIS .7. SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS WITH AFFINITY-CHROMATOGRAPHIC SEPARATION OF PRODUCT
SELIGER, H
HOLUPIREK, M
GORTZ, HH
TETRAHEDRON LETTERS, 1978, (24) : 2115 - 2118
[30] Immobilization of pectinase on reusable polymer support for clarification of apple juice
Rajdeo, Kishor
Harini, Tirunagari
Lavanya, Kuna
Fadnavis, Nitin W.
FOOD AND BIOPRODUCTS PROCESSING, 2016, 99 : 12 - 19

← 1 2 3 4 5 →