Visualizing heterogeneity in type 2 diabetes phenotype, outcome and drug response

被引：1
|
作者：
Pearson, Ewan [1 ]
Thakarakkattil, Anand [1 ]
Nair, Narayanan [1 ]
机构：
[1] Univ Dundee, Dundee, Scotland
来源：
NATURE MEDICINE | 2022年 / 28卷 / 05期
关键词：
D O I：
10.1038/s41591-022-01791-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Phenotypic heterogeneity in type 2 diabetes (T2D) was visualized by non-linear dimensionality reduction in a cohort of over 23,000 people. Variation in the T2D phenotype mapped to variation in drug response, risk of disease complications and underlying genetic architecture.
引用
收藏
页码：909 / 910
页数：2
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