Dose distributions for 90Y intravascular brachytherapy sources used with balloon catheters

被引:6
|
作者
Piessens, M
Reynaert, N
Potempa, J
Thierens, H
Wijns, W
Verbeke, L
机构
[1] Onze Lieve Vrouw Hosp, Dept Radiat Therapy & Oncol, B-9300 Aalst, Belgium
[2] Univ Ghent, Stand Dosimetry Lab, B-9000 Ghent, Belgium
[3] MDS Nordion Haan GmbH, D-42781 Haan, Germany
[4] Onze Lieve Vrouw Hosp, Ctr Cardiovasc, B-9300 Aalst, Belgium
关键词
intravascular brachytherapy; Y-90; Monte Carlo; beta dosimetry; detector intercomparison;
D O I
10.1118/1.1488604
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The dose distribution around an intravascular brachytherapy Y-90 line source with centering balloon catheters was measured with a plastic scintillator, TLD and radiochromic film. The absolute dose rates measured with the three detectors in a solid water phantom at 1, 2 and 3 mm distance from the centering balloon surfaces are in agreement within 3.5%, when the detectors are calibrated with the same Sr-90/Y-90 source, The dose rates measured with the plastic scintillator in the solid water phantom are in agreement with those directly measured in water. The measured relative dose distributions can be reproduced by Monte Carlo calculations. Also, the influence of the balloon diameter on the dose rate can be reproduced by the calculations. The dose rate calibration routinely performed with the plastic scintillator was checked for fifty-one sources with a well chamber and with another dedicated dose rate checking device. These measurements show that the consistency of the calibration of these sources was better than 10%. In a previous paper absolute dose rates for five other 90Y sources measured with TLD and radiochromic film in a solid water phantom were compared with those obtained with the plastic scintillator in water [Piessens and Reynaert, "Verification of absolute dose rates for intravascular beta sources," Phys. Med. Biol. 45, 2219-2231 (2000)]. Differences of 25 to 41%. depending on the balloon diameter, were reported, In this paper we show the evidence for three main reasons for these previously observed discrepancies: an inconsistency between a detector calibration performed with a 6 MeV electron beam and with a calibrated Sr-90/Y-90 source from NIST (16%), inaccuracies of the measuring distances in the solid water phantom (maximum 7.5%) and a time instability of the plastic scintillator, probably due to radiation damage (6%). (C) 2002 American Association of Physicists in Medicine.
引用
收藏
页码:1562 / 1571
页数:10
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