Modeling Pediatric Epilepsy Through iPSC-Based Technologies

被引：21
|
作者：
Simkin, Dina [1 ,2 ]
Kiskinis, Evangelos [1 ,3 ]
机构：
[1] Northwestern Univ, Feinberg Sch Med, Ken & Ruth Davee Dept Neurol, 303 East Chicago Ave,Ward 12-140, Chicago, IL 60611 USA
[2] Northwestern Univ, Dept Pharmacol, Feinberg Sch Med, Chicago, IL 60611 USA
[3] Northwestern Univ, Feinberg Sch Med, Dept Physiol, Chicago, IL 60611 USA
来源：
EPILEPSY CURRENTS | 2018年 / 18卷 / 04期
关键词：
PLURIPOTENT STEM-CELLS; HUMAN BRAIN-DEVELOPMENT; ILAE COMMISSION; NEURONS; DISORDERS; SEIZURE; INDUCTION; ANGELMAN; CHANNELS; REVEALS;
D O I：
10.5698/1535-7597.18.4.240
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In the current review, we discuss the process of modeling pediatric epileptic encephalopathies with a focus on in vitro iPSC-based technologies. We highlight the potential benefits as well as the challenges of these approaches and propose appropriate standards for the field.
引用
收藏
页码：240 / 245
页数：6
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